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Výsledek výzkumu

A novel bifunctional multilayered nanofibrous membrane combining polycaprolactone and poly (vinyl alcohol) enriched with platelet lysate for skin wound healing

Skin wound healing is a complex physiological process that involves various cell types, growth factors, cytokines, and other bioactive compounds. In this study, a novel dual-function multilayered nanofibrous membrane is developed for chronic wound ap...

Materials engineering

  • 2024
  • Jimp
  • Odkaz
Výsledek výzkumu

Comparative Study of the Dehydrothermal Crosslinking of Electrospun Collagen Nanofibers: The Effects of Vacuum Conditions and Subsequent Chemical Crosslinking

Collagen nanofibrous materials have become integral to tissue engineering due to their exceptional properties and biocompatibility. Dehydrothermal crosslinking (DHT) enhances stability and maintains structural integrity without the formation of toxic...

Polymer science

  • 2024
  • Jimp
  • Odkaz
Výsledek výzkumu

The Impacts of the Sterilization Method and the Electrospinning Conditions of Nanofibrous Biodegradable Layers on Their Degradation and Hemocompatibility Behavior

The use of electrospun polymeric biodegradable materials for medical applications is becoming increasingly widespread. One of the most important parameters regarding the functionality of nanofiber scaffolds during implantation and the subsequent rege...

Biomaterials (as related to medical implants, devices, sensors)

  • 2024
  • Jimp
  • Odkaz
Výsledek výzkumu

An absorbable composite bandage from polymer reinforcement and collagen matrix

The present technical solution relates to an absorbable composite bandage comprising a polymeric or copolymeric electrically softened reinforcement and a collagen matrix for use in cardiac surgery and traumatology....

Nano-materials (production and properties)

  • 2024
  • Fuzit
Výsledek výzkumu

Mechanical Properties of Collagen-Poly-lactide/caprolactone Composite for Pulmonary Artery Banding

Pulmonary artery banding is a surgical procedure used in neonates to induce a mechanobiological response, leading to natural repair of certain congenital heart defects. Current banding methods involve a two-step procedure that requires the use of a n...

Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

  • 2024
  • D
  • Odkaz
Výsledek výzkumu

Experimental surgery as part of the development of degradable biomaterials for cardiovascular surgery

ntroduction: Cardiovascular diseases are responsible for significant morbidity and mortality in the population. Artificial vascular grafts are often essential for surgical procedures in radical or palliative treatment. Many new biodegradable material...

Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

  • 2022
  • JSC
  • Odkaz
Výsledek výzkumu

Effect of humidity during electrospinning of biodegradable polyester nanofibers

Among widely electrospun biodegradable polymer materials are aliphatic polyesters: polycaprolactone, polylactide acid or a copolymer of caprolactone and lactic acid (PLCL). Many different modifications of electrospinning can be used to change the fib...

Nano-materials (production and properties)

  • 2022
  • D
  • Odkaz
Výsledek výzkumu

Use of a Silver-impregnated Vascular Graft: Single-Center Experience

Introduction: Vascular graft infection is a life threatening situation with significant morbidity and mortality. Bacterial graft infection can lead to false aneurysms, bleeding and sepsis. There are a lot of risky situations where grafts can become i...

Biological sciences

  • 2022
  • Jimp
  • Odkaz
Výsledek výzkumu

Bevacizumab Does Not Inhibit the Formation of Liver Vessels and Liver Regeneration Following Major Hepatectomy: A Large Animal Model Study

Background/Aim: Patients with unresectable liver colorectal cancer metastases are treated with neoadjuvant chemotherapy often accompanied by biological therapy aimed at reducing the mass of metastases and thus increasing the chances of resectability....

Surgery

  • 2022
  • Jimp
  • Odkaz
Výsledek výzkumu

Functional responses of dermal fibroblasts to low nutrition and pro-inflammatory stimuli mimicking a wound environment in vitro

Dermal fibroblasts (DF) constitute one of key cells involved in wound healing. However, the functions they perform in wound conditions remain poorly understood. This study involved exposing DF to low nutrition and to low nutrition + LPS for 5 d as co...

Biological sciences

  • 2022
  • Jimp
  • Odkaz
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