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288 867 (0,236s) •

Projekt

Effects of drugs on radiation induced damages of DNA (IAB1048901)

of free radicals produced by the radioation in DNA surrounding. Our recently developed of radicals) and Smoluchowski theory (chemical reactions of radicals with ligands and DNA).The thre...

BO - Biofyzika

  • 1999 - 2000
    • •
  • 282 tis. Kč
    • •
  • 226 tis. Kč
    • •
  • AV ČR
Projekt

Effects of ligands on DNA damage induced by free radicals. (OC09012)

. The existing stochastic model of DNA damage caused by free radical attack will be furtherDNA attack by radical species produced by water radiolysis is the most is to follow yields and d...

BO - Biofyzika

  • 2009 - 2011
    • •
  • 465 tis. Kč
    • •
  • 465 tis. Kč
    • •
  • MŠMT
Projekt

Radiolytic damage of DNA bases (KJB4048401)

Oxidative damage of DNA bases belongs to the most severe DNA damages caused, nucleosides and short DNA oligomers. The diffusion of radicals produced by water is to establish differences i...

CE - Biochemie

  • 2004 - 2005
    • •
  • 278 tis. Kč
    • •
  • 278 tis. Kč
    • •
  • AV ČR
Výsledek výzkumu

Free radicals, antioxidants and ageing

Free radical theory of ageing and damage to mitochondrial DNA is discussed. Free radicals also cause many diseases with the highest incidence just in order people....

FP - Ostatní lékařské obory

  • 2003
    • •
  • Jx
Výsledek výzkumu

Radiomodifying effects of RAPTA C and CDDP on DNA strand break induction

to DNA damage caused by products of radiolysis of RAPTA C or CDDP is negligible in comparison to the damage caused by products of radiolysis of water. After binding to DNA caused by enha...

Physical chemistry

  • 2017
    • •
  • Jimp
    • •
  • Odkaz
Projekt

Ischaemia reperfusion injury in accute myocardial infarction (NT13709)

. Oxidative damage of DNA caused by free oxygen radicals, measurable in lymphocytes with comet assay, can establish reperfusion injury. Measurement of DNA damage in coronaryMyocardial inj...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2012 - 2014
    • •
  • 2 778 tis. Kč
    • •
  • 2 778 tis. Kč
    • •
  • MZ
Projekt

Mechanisms of DNA damage checkpoint termination (GAP301/10/1525)

Cells react to genotoxic stress by activating surveillance mechanisms organized in DNA damage response pathways (DDR) and arrest cell cycle progression (checkpoint) to allow time for DNA repair. Undesired propagation of mut...

FD - Onkologie a hematologie

  • 2010 - 2012
    • •
  • 3 507 tis. Kč
    • •
  • 3 507 tis. Kč
    • •
  • GA ČR
Projekt

Radiation induced damage of DNA - protein complexes (IAA1048103)

ofradiation-induced damages. Probabilities of radical reactions with DNA and proteins radical diffusion) and Smoluchowski theory (radical reactions with DNA). We proposeThe project includes theor...

BO - Biofyzika

  • 2001 - 2003
    • •
  • 1 543 tis. Kč
    • •
  • 738 tis. Kč
    • •
  • AV ČR
Výsledek výzkumu

Oxidative stress after therapeutic laser and gamma irradiation

the presence of products of the damage to molecules with free radicals, among others to the DNA. The antioxidants are chemical compounds that can bind to free oxygen radicals preventing these

FI - Traumatologie a ortopedie

  • 2009
    • •
  • D
Výsledek výzkumu

Theoretical Modeling of Radiation Damage of DNA Bases

Theoretical model RADACK has been applied for predictions of yields of OH* radical reactions with individual free bases, nucleotides and short DNA fragments. The influence of atom accessibility to OH* radicals and ...

BG - Jaderná, atomová a molekulová fyzika, urychlovače

  • 2005
    • •
  • D
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