Filtry
Two subsets of stem-like CD8(+)memory T cell progenitors with distinct fate commitments in humans
(TIGIT) were committed to a functional lineage, whereas progenitors expressing PD-1 and TIGIT were committed to a dysfunctional, exhausted-like lineage. Collectively......
Immunology
- 2020 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
New potential checkpoint inhibitors in cancer therapy
Over the last decade, immunotherapy has been established as part of various treatment algorithms across solid tumors. And although the use of checkpoint inhibitors like anti-PD-1 and anti-CTLA-4 receptors and anti-PD-1 ligand provides a therapeutic b...
Oncology
- 2022 •
- JSC •
- Odkaz
Rok uplatnění
JSC - Článek v periodiku v databázi SCOPUS
Výsledek na webu
TIM-3 levels correlate with enhanced NK cell cytotoxicity and improved clinical outcome in AML patients
Accumulating evidence indicates that immune checkpoint inhibitors (ICIs) can restore CD8(+) cytotoxic T lymphocyte (CTL) functions in preclinical models of acute myeloid leukemia (AML). However, ICIs targeting programmed cell death 1 (PDCD1, best kno...
Microbiology
- 2021 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Characterization of the input material quality for the production of tisagenlecleucel by multiparameter flow cytometry and its relation to the clinical outcome
(CD45RA, CD62L, CD27, CD28) and the expression of inhibitory receptors (PD-1, TIGIT...
Hematology
- 2023 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Distinct CD8 T Cell Populations with Differential Exhaustion Profiles Associate with Secondary Complications in Common Variable Immunodeficiency
of CD127 and CD28, and expression of TIGIT and PD-1 in CD8 T cells are strongly...
Immunology
- 2022 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
OMIP-106: a 30-color panel for analysis of check-point inhibitory networks in the bone marrow of acute myeloid leukemia patients
of their phenotype with regard to their differentiation, expression of inhibitory (PD-1, TIGIT...
Hematology
- 2024 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Immune Checkpoints and Their Inhibition in T-Cell Lymphomas
T-cell lymphomas (TCLs) are a rare and heterogeneous subgroup of non-Hodgkin lymphomas (NHLs), forming only 10 % of all NHL cases in Western countries. Resulting from their low incidence and heterogeneity, the current treatment outcome is generally u...
Oncology
- 2024 •
- Jimp •
- Odkaz
Rok uplatnění
Jimp - Článek v periodiku v databázi Web of Science
Výsledek na webu
Role of cytotoxic gamma-delta T cells in therapeutic resistance and recurrence of Glioblastoma Multiforme
by flow cytometry for the expression of NKG2D, DNAM1, TIGIT, PD-1 and Tim3 receptors...
Oncology
- 2021 •
- O •
- Odkaz
Rok uplatnění
O - Ostatní výsledky
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