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8 871 (0,091s) •

Projekt

Dendritic cell based cancer immunotherapy of prostate cancer Phase I/II clinical trial (NT11559)

We developed a dendritic cell-based vaccine for cancer immunotherapy. In this project, we plan to run a Phase I/II clinical trial in patients with prostate cancer either at the stage of the biochemical relapse or with hormo...

EC - Imunologie

  • 2010 - 2014
    • •
  • 10 650 tis. Kč
    • •
  • 10 650 tis. Kč
    • •
  • MZ
Projekt

Czech National Node to the European Clinical Research Infrastructure Network (LM2015090)

and control activities for academic clinical trials and clinical studies iniciated by academic researchers of any expertise, theoretically, whichever research phase knowledge, research coordination, education and ...

FR - Farmakologie a lékárnická chemie

  • 2016 - 2019
    • •
  • 49 864 tis. Kč
    • •
  • 49 864 tis. Kč
    • •
  • MŠMT
Projekt

Dendritic cell based cancer immunotherapy of ovarian cancer Phase I/II clinical trial (NT12402)

We developed a dendritic cell-based vaccine for cancer immunotherapy. In this project, we plan to run a Phase I/II clinical trial in patients in the stage III-IV of ovarian cancer according the FIGO (International Federatio...

EC - Imunologie

  • 2011 - 2015
    • •
  • 9 655 tis. Kč
    • •
  • 9 655 tis. Kč
    • •
  • MZ
Projekt

Advanced Cell Immunotherapy Unit - ACIU (LM2011017)

and organs. 3. Phase I/II clinical trials in perspective therapeutic preparations and technology transfer for implementation of modern immunotherapeutics in the clinic.......

FD - Onkologie a hematologie

  • 2012 - 2016
    • •
  • 23 500 tis. Kč
    • •
  • 18 500 tis. Kč
    • •
  • MŠMT
Projekt

Overcoming P-glycoprotein-mediated multidrug resistance (MDR) (GA310/99/P020)

). Doxorubicin conjugated to HPMA has entered Phase II. clinical trial in UK, galactosamine-targeted conjugate just finished Phase I. clinical trial. 2) There are many......

EC - Imunologie

  • 1999 - 2001
    • •
  • 792 tis. Kč
    • •
  • 719 tis. Kč
    • •
  • GA ČR
Projekt

The treatment of chronic spinal cord injury using stem cells and enzymes in combination with polymer scaffolds (GA13-00939S)

will be selected, and its certification along with a clinical trial will be prepared.The chronic phase of spinal cord injury (SCI) presents a major challenge remain in this phase for life. Despite several successf...

FH - Neurologie, neurochirurgie, neurovědy

  • 2013 - 2016
    • •
  • 10 360 tis. Kč
    • •
  • 10 360 tis. Kč
    • •
  • GA ČR
Projekt

Nanoparticle formulation of copper dithiocarbomate for the cancer treatment (FW04020197)

The main aim of this project is to obtain and characterize of anticancer drug’s (nano-CuET) prototype for launching a clinical trial That means: 1. formulation and certification of necessary analytical methods 3. ...

Pharmacology and pharmacy

  • 2022 - 2024
    • •
  • 20 774 tis. Kč
    • •
  • 11 235 tis. Kč
    • •
  • TA ČR
Projekt

Sentinel lymph node biopsy versus systematic pelvic lymphadenectomy in patients with early stages cervical cancer (NV16-31643A)

for phase III clinical trial including randomization, central quality assurance and clinical monitoring. The trial has a realistic potential to reach a calculated number. However, SLN biopsy is still not ...

FK - Gynekologie a porodnictví

  • 2016 - 2019
    • •
  • 6 607 tis. Kč
    • •
  • 6 607 tis. Kč
    • •
  • MZ
Projekt

Anti-tumour therapy - vaccination with dendritic cells in patients with metastatic renal cell carcinoma. Phase II clinical study. (NT11137)

overall survival 12 months. Proposed project - an investigator driven randomized phase II clinical study - would like to test the benefit of a novel vaccine based Control to produce dendritic cell vaccines for clinical app...

FD - Onkologie a hematologie

  • 2010 - 2013
    • •
  • 5 619 tis. Kč
    • •
  • 5 619 tis. Kč
    • •
  • MZ
Projekt

Mitochondrially targeted tamoxifen in renal cancer treatment (NU21-03-00545)

or partial remission). Expecting a positive outcome of Phase 1 clinical trial, we plan to launch Phase 2 trial, most likely towards the end of 2021 or during 2022, and is currently under Phase 1/...

Cell biology

  • 2021 - 2024
    • •
  • 14 900 tis. Kč
    • •
  • 14 900 tis. Kč
    • •
  • MZ
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