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Filtry

4 375 (0,079s) •

Projekt

Studies of genetic associations of female reproductive disorders of autoimmune origin HLA class II and CTLA-4 genes (NH6451)

Study on associations of polymorphisms of HLA class II and CTLA-4 gene with female infertility positive for autoantibodies to zona pellucida and/or antiphospholipid autoantibodies.......

FK - Gynekologie a porodnictví

  • 2001 - 2003
    • •
  • 1 459 tis. Kč
    • •
  • 1 444 tis. Kč
    • •
  • MZ
Projekt

An effect of HLA-DP incompatibilities on the outcome of hematopoietic stem cell transplantation. (NR7984)

Retrospective study: Exactly defined mismatches between an unrelated donor and the recipient of HSC in HLA-DP and HLA-A, -B, -C, -DRB1, -DQB1 will be evaluated with different parameters of the transplantation outcome. Persp...

FJ - Chirurgie včetně transplantologie

  • 2004 - 2006
    • •
  • 3 415 tis. Kč
    • •
  • 3 298 tis. Kč
    • •
  • MZ
Projekt

The role of the hypocretine in pathophysiology of primary dyssomnias - Immunological and neurovegetative aspects. Neuroanatomical corelates (GP309/03/P026)

in the brain of HLA DQB1*0602 positive narcoleptic patients suggest that these cells may be aprimarytarget for this process. HLA association studies in patients without cataplexy indicated lower HLA DQB1*0602 ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2003 - 2005
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  • 631 tis. Kč
    • •
  • 631 tis. Kč
    • •
  • GA ČR
Projekt

Contribution to improved diagnosis and pathogenesis in autoimmune HKA associated diseases. (IZ3647)

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1996 - 1998
    • •
  • 2 521 tis. Kč
    • •
  • 2 521 tis. Kč
    • •
  • MZ
Projekt

Polymorphisms in the NK cells receptors and their ligands within the Czech population (NV18-03-00277)

introduced a selection based on other criteria than the commonly used HLA match. Match, the standard HLA criterion is HLA match and HLA-DPB permissive, and in some diseases......

Oncology

  • 2018 - 2021
    • •
  • 15 172 tis. Kč
    • •
  • 15 172 tis. Kč
    • •
  • MZ
Projekt

Implementation of high-performance liquid chromatography (HPLC) to the molecular testing of inherited haemostatic defects and to the histocompatibility tests for haematopoietic stem cell transplantation (HSCT). (NM7615)

variants by means of HPLC. The human genom loci involved will be FVIII gene and HLA-A, -B, -C and -DRB1. To identify causal mutations in index patients with haemophilia. To increase discrimination of the HLA genotyping whe...

FD - Onkologie a hematologie

  • 2003 - 2005
    • •
  • 3 863 tis. Kč
    • •
  • 3 683 tis. Kč
    • •
  • MZ
Projekt

Immunogenetic molecular profile of sarcoidosis significance for disease course prediction (NV18-05-00134)

in the immune genes including those of HLA complex in the development / clinical course of pulmonary sarcoidosis. Recent methods allowing detailed discrimination of HLA alleles/haplotypes (NGS) will be utilised and comparisons will...

Epidemiology

  • 2018 - 2022
    • •
  • 8 412 tis. Kč
    • •
  • 8 330 tis. Kč
    • •
  • MZ
Projekt

Diagnostics of antibody-mediated rejection after liver transplantation (NV16-27477A)

Antibody-mediated rejection (AMR) is a severe immunological complication in transplant patients, which is associated with production of antibodies against HLA is to contribute to the clarification of the clinical relevance of HL...

EC - Imunologie

  • 2016 - 2019
    • •
  • 8 138 tis. Kč
    • •
  • 8 138 tis. Kč
    • •
  • MZ
Projekt

Type 1 diabetes mellitus and associated autoimmune diseases. (NB6278)

Screening and diagnosis of associated autoimmune disease in patients with type I diabetes. Immunogenetic, immunological, clinical characteristics. Analysis of circulating organ specific autoantibodies. Early diagnosis.......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2000 - 2002
    • •
  • 2 059 tis. Kč
    • •
  • 2 059 tis. Kč
    • •
  • MZ
Projekt

Clinical and prognostic significance of BAFF (B-cell activating factor) and its receptors in idiopatic inflammatory myopathies (NT12438)

a) Quantitative analysis of serum levels of BAFF (B cell activating factor mechanisms of idiopathic inflammatory myopathies in relation to disease activity. b protein with assessment of the extent of correlation with risk HLA

FE - Ostatní obory vnitřního lékařství

  • 2011 - 2014
    • •
  • 5 276 tis. Kč
    • •
  • 5 276 tis. Kč
    • •
  • MZ
  • 1 - 10 z 4 375