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2 157 (0,068s) •

Projekt

Complex structural analysis of interaction at the protein - nucleic acid interface by unique bioinformatic descriptors (MEB021032)

We propose a complex analysis of the protein-nucleic acid (NA) interface by use of unique tools of structural bioinformatics developed in the collaborating labs. We in the recognition process may lead to damage or death of ...

BO - Biofyzika

  • 2010 - 2011
    • •
  • 106 tis. Kč
    • •
  • 106 tis. Kč
    • •
  • MŠMT
Projekt

Protonation and coordination states critical for metallonuclease catalysis (GA25-17546S)

-nucleic acid interactions plays an essential role in recognition and catalysis. Localization of hydrogens in protein- nucleic acid complexes has not been studied and nucleic acids in dep...

Biophysics

  • 2025 - 2027
    • •
  • 5 712 tis. Kč
    • •
  • 5 712 tis. Kč
    • •
  • GA ČR
Projekt

Properties of mesoporous silica and ability to interactions with nucleic acids (7AMB13PL011)

, functionalized for nucleic acid binding and single/double stranded nucleic acids the physicochemical properties of mentioned MSN alone and complexed with nucleic acids 3, functionalisation) and ...

BO - Biofyzika

  • 2013 - 2014
    • •
  • 135 tis. Kč
    • •
  • 135 tis. Kč
    • •
  • MŠMT
Projekt

Application of adsorptive transfer and elemination techniques in oligonucleotides and nucleic acids analysis. (IAA1163201)

of detecting of nucleic acids bases using transfer technique in connection with elimination and electrochemical impedance spectroscopy in oligonucleotides and nucleic acids analysis analytical procedures for the d...

BO - Biofyzika

  • 2002 - 2004
    • •
  • 1 481 tis. Kč
    • •
  • 1 251 tis. Kč
    • •
  • AV ČR
Projekt

Nucleic Acid Regulatory Sequences - polymorphism, dynamics, and interactions (GA15-06785S)

types of nucleic acid regulatory sequences - DNA guanine quadruplexes, miRNA. The nucleic acid segments and/or their complexes with key proteins will be studied of nucleic acids.......

BO - Biofyzika

  • 2015 - 2017
    • •
  • 11 631 tis. Kč
    • •
  • 11 631 tis. Kč
    • •
  • GA ČR
Projekt

New trends in electrochemistry of nucleic acids and their applications in enviromental chemistry (GA203/02/0422)

tostudy oligonucleotides and nucleic acids and then-interactions with some drugs studies will concentrate also on interaction of the nucleic acids strands at the electrode surface aimed for developing sensors for ...

CG - Elektrochemie

  • 2002 - 2004
    • •
  • 4 167 tis. Kč
    • •
  • 2 790 tis. Kč
    • •
  • GA ČR
Projekt

Theoretical and spectroscopic studies of nucleic acid self-assemblies (GAP208/10/0559)

Nucleic acid self-assemblies attract attention because of their intrigue nature and theoretical procedures allowing classifying various types of nucleic acid self-assemblies are proposed. Multiple-stranded nucl...

CF - Fyzikální chemie a teoretická chemie

  • 2010 - 2012
    • •
  • 2 437 tis. Kč
    • •
  • 2 437 tis. Kč
    • •
  • GA ČR
Projekt

Study of Effects of Intermolecular Interactions on the Character of Electronically Excited States of Nucleic Acids Bases (GAP208/12/1318)

The project includes the study of the nature of nucleic acid bases in their electronically excited states. Large models of nucleic acids which account for interactions of nucleic acid bases in the...

CF - Fyzikální chemie a teoretická chemie

  • 2012 - 2014
    • •
  • 1 705 tis. Kč
    • •
  • 1 705 tis. Kč
    • •
  • GA ČR
Projekt

Tetrapyrrole Metallocomplexes for Modification of Triplex DNA Structures (GA203/02/0420)

-stranded nucleic acids will be studied by combination of spectroscopic methods - UV/Vis technique will afford kinetic description of metallocomplex - nucleic acid interactions of multistranded structures of nu...

CA - Anorganická chemie

  • 2002 - 2004
    • •
  • 8 916 tis. Kč
    • •
  • 3 114 tis. Kč
    • •
  • GA ČR
Projekt

Toward Improved Description of Nucleic Acid Backbone Developing Force Field Torsion Parameters. (GP14-29874P)

Accurate representation of nucleic acids in molecular dynamics simulations witnessed severe problems in describing the torsion space in nucleic acids by current simulations of various nucleic acid...

CF - Fyzikální chemie a teoretická chemie

  • 2014 - 2016
    • •
  • 1 335 tis. Kč
    • •
  • 1 335 tis. Kč
    • •
  • GA ČR
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