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13 363 (0,092s) •

Projekt

The interaction between renin-angiotensin and endothelin systems in the pathogenesis of renal failure and cardiac hypertrophy in hypertensive rats (NS10500)

Potential additive effect of the treatment wirh endothelin receptor blocker (atrasentan) to low salt diet and renin-angiotensin system blockade in a rat model transenic for mouse renin gene and/or 5/6 nephrectomy will be studied. The aim is ...

FE - Ostatní obory vnitřního lékařství

  • 2009 - 2011
    • •
  • 3 942 tis. Kč
    • •
  • 3 942 tis. Kč
    • •
  • MZ
Projekt

Molecular classification of renal cell carcinoma based on long non-coding RNAs expression and its implication for diagnosis, prognosis and therapy (NV18-03-00554)

Renal cell carcinoma (RCC) is the most common cancer of adult kidney. Despite advances in diagnosis, about 20–30% of all patients are diagnosed with metastatic disease. In addition, another 20% of patients undergoing nephrectomy will have, t...

Oncology

  • 2018 - 2022
    • •
  • 11 932 tis. Kč
    • •
  • 11 881 tis. Kč
    • •
  • MZ
Projekt

Etiopathogenetic role and prognostic significance of PAX 2 and PAX 8 expression and microsatelite instability on chromosome 3 and 9 in renal cell carcinoma (NC7519)

. The tumor tissue will be obtained during nephrectomy or partial kidney resection...

FD - Onkologie a hematologie

  • 2003 - 2005
    • •
  • 2 185 tis. Kč
    • •
  • 2 185 tis. Kč
    • •
  • MZ
Projekt

Anti-tumour therapy - vaccination with dendritic cells in patients with metastatic renal cell carcinoma. Phase II clinical study. (NT11137)

with standard treatment (nephrectomy followed by sunitinib) and another half of patients...

FD - Onkologie a hematologie

  • 2010 - 2013
    • •
  • 5 619 tis. Kč
    • •
  • 5 619 tis. Kč
    • •
  • MZ
Projekt

Macrophage polarization and the fatty acid spectrum of cell membrane phospholipids of adipose tissue (NU20-01-00022)

-assisted laparoscopic nephrectomy of 60 living kidney donors (LKDs). In a group of LKDs...

Endocrinology and metabolism (including diabetes, hormones)

  • 2020 - 2023
    • •
  • 4 242 tis. Kč
    • •
  • 4 242 tis. Kč
    • •
  • MZ
Projekt

Mitochondrial respiratory complex II aberrations as complication in renal cancer therapy based on mitochondrial targeting (NU23-03-00226)

model of ccRCC. In this project, we will combine methods of gene manipulation and derived primary cell cultures obtained after nephrectomy. In case we find......

Biochemistry and molecular biology

  • 2023 - 2026
    • •
  • 12 546 tis. Kč
    • •
  • 12 546 tis. Kč
    • •
  • MZ
Projekt

Pharmacological blockade of both the endothelin system and soluble epoxyde hydrolase as a new aproach to the treatment of hypertensive organ damage (NV15-28671A)

)27 hypertensive rats (TGR) after 5/6 nephrectomy (5/6NX) will be treated...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2015 - 2019
    • •
  • 8 880 tis. Kč
    • •
  • 8 880 tis. Kč
    • •
  • MZ
Projekt

Usage of genetic transforation and molecular markers in development of new kinds of flax. (ME 703)

Methods of transer else gens to genom of flax,methods of selection transformed plants and methods of identification transformants with method PCR development.Further usage of materials will be also determined.......

GE - Šlechtění rostlin

  • 2003 - 2004
    • •
  • 798 tis. Kč
    • •
  • 562 tis. Kč
    • •
  • MŠMT
Projekt

Prediction of Solubility for Large Molecules in Solvents by Parallelized Molecular Simulation Methods (IAA4072309)

We will develop parallelized simulation methods for calculation of chemical potential of large molecules. The parallelized simulation method will be developed on the basis of advanced simulation methods such as the Kirkwood...

CF - Fyzikální chemie a teoretická chemie

  • 2003 - 2005
    • •
  • 1 529 tis. Kč
    • •
  • 1 309 tis. Kč
    • •
  • AV ČR
Projekt

High Performance Computing in Geosciences (OK 383)

The project is devoted to the development of mathematical methods which enable methods include adaptive finite element methods, composite grid finite element methods, iterative methods of conjugate gradien...

BA - Obecná matematika

  • 1999 - 2001
    • •
  • 805 tis. Kč
    • •
  • 355 tis. Kč
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  • MŠMT
  • 1 - 10 z 13 363