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Projekt

IVD PROBES (TH03010251)

part aims at development of new IVD kits for detection of mutations causing resistance or impaired response for oncological treatment. In developing these kits we will use knowledge gained from first part of project. Aim o...

Human genetics

  • 2018 - 2021
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  • 20 826 tis. Kč
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  • 12 494 tis. Kč
    • •
  • TA ČR
Projekt

Development of diagnostic kits for the prediction of the disorders of myorelaxans metabolism at anesteziology and intensive medicine (TH04010116)

no predictive CE-IVD kit is available on the market. This genetic testing is performed by non-standard home-made kits. This is a clear sign, that the market for setsThe purpouse of this project is to develop within 3 years...

Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])

  • 2019 - 2022
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  • 21 800 tis. Kč
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  • 13 048 tis. Kč
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  • TA ČR
Projekt

Diagnostics of cancer with Next Generation Sequencing (TA04010838)

Main focus of project is development and verification of kit for preparation of genetic libary for next generation sequencing (NGS), which allows detail genetic diagnostics of colorectal cancer (CRC) and NSCLC (Non Small Cell Lung C...

EB - Genetika a molekulární biologie

  • 2014 - 2017
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  • 19 053 tis. Kč
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  • 12 356 tis. Kč
    • •
  • TA ČR
Projekt

The development of genetic tests for pharmacogenetics and personalized medicine (TA04011330)

The main objective of the project is to develop prototypes of kits for detection of changes in human DNA that cause variable drug response. The prototypes of diagnostics kits are going to be the main result of the kit and t...

EB - Genetika a molekulární biologie

  • 2014 - 2017
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  • 16 870 tis. Kč
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  • 10 897 tis. Kč
    • •
  • TA ČR
Projekt

Development of a kit for detection of mutations in structural proteins of a cell (FR-TI3/588)

description of mutations or polymorphisms in genes coding for structural proteins linked. The developed diagnostic kit will enable or improve diagnostics of these diseases......

EB - Genetika a molekulární biologie

  • 2011 - 2015
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  • 48 858 tis. Kč
    • •
  • 37 860 tis. Kč
    • •
  • MPO
Projekt

Develoment of analyzer for needs of up to date molecular genetic diagnostic tests (FR-TI3/408)

is to develop diagnostic kits for own diagnostic kits from other vendor as well...

FS - Lékařská zařízení, přístroje a vybavení

  • 2011 - 2015
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  • 36 800 tis. Kč
    • •
  • 17 260 tis. Kč
    • •
  • MPO
Projekt

Screening of mutations in the non-duplicated region of the PKD1 gene from families with autosomal dominant polycystic kidney disease (NE7633)

Analysis of mutations in non-duplicated region of the PKD1 gene in selected families with ADPKD by screening methods (SSCP,HA,DGGE) and following sequencing of positive fragments.......

EB - Genetika a molekulární biologie

  • 2003 - 2005
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  • 3 439 tis. Kč
    • •
  • 3 364 tis. Kč
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  • MZ
Projekt

Promoter methylation analysis of the genes downstream of BRCA1 and BRCA1 - comparison of methylation profiles in mutation carriers and non-carriers (GP301/08/P103)

Different penetrance of identical mutations is observed in BRCA1/2 genes mutation carriers. There is an extensive search for cancer risk modifier factors time.The expression profile difference of BRCA1/2 mutation carriers a...

EB - Genetika a molekulární biologie

  • 2008 - 2010
    • •
  • 1 563 tis. Kč
    • •
  • 1 563 tis. Kč
    • •
  • GA ČR
Projekt

New generation of construction kits for technical education. (TA03011254)

The main goal is to develop an innovative construction kits Merkur-Profi. The construction kits will be used as tools for an improvement of education in technical fields with a potential use in professional field. These kits

JQ - Strojní zařízení a nástroje

  • 2013 - 2015
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  • 12 090 tis. Kč
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  • 7 700 tis. Kč
    • •
  • TA ČR
Projekt

Unknown cause of DFNB1 deafness in patients with only one pathogenic GJB2 gene mutation – complex elucidation by new molecular genetic approaches. (NV16-31921A)

) is found despite testing for other known factors (mutation in non-coding exon 1Early non-syndromic hearing loss is a major health concern. Inheritance that mutations in the GJB2 gene cause up to 40 % of early non...

FF - ORL, oftalmologie, stomatologie

  • 2016 - 2020
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  • 5 531 tis. Kč
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  • 5 456 tis. Kč
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  • MZ
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