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10 338 (0,103s) •

Projekt

The study of analytical properties of the metabolits of melatonin in urine for gerontological and clinical research (GP203/01/D139)

At present time melatonin has been intensively studied among others for its expected activity as free radical scavenger. The potential ability of melatonin to moderate the unfarourable results of the action of ...

CB - Analytická chemie, separace

  • 2001 - 2003
    • •
  • 994 tis. Kč
    • •
  • 479 tis. Kč
    • •
  • GA ČR
Projekt

The role and mechanism of action of free radicals in the pathogenesis and therapy of the pain. (NF4665)

of free radicals, espec. the singlet oxygen, nitroxide radical and other ROSThe effect of subst. with antioxidat. and scavenger effect (melatonin, PBN) and their possible potent. of the effect of analgetic drugs w...

FH - Neurologie, neurochirurgie, neurovědy

  • 1998 - 2000
    • •
  • 1 244 tis. Kč
    • •
  • 1 219 tis. Kč
    • •
  • MZ
Projekt

Single-atom platinum decorated cerium oxide as nanozymes against oxidative stress (8J23FR026)

The proposal aims to design ROS-scavenging nanozymes possessing excellent free radical scavenging properties to regulate intracellular ROS. Antioxidants are capable of scavenging free radicals...

Inorganic and nuclear chemistry

  • 2023 - 2024
    • •
  • 156 tis. Kč
    • •
  • 156 tis. Kč
    • •
  • MŠMT
Projekt

The role of steroid sulfates in steroid metabolism and their diagnostic meaning. (NB5398)

Investigation of influencing the kinetics of formation and matabolism of steroid sulfates by free radical scavengers and diagnostic utilization of possible relation between autoimunne diseases and plasma levels of steroid s...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 1999 - 2001
    • •
  • 2 377 tis. Kč
    • •
  • 1 888 tis. Kč
    • •
  • MZ
Projekt

Antioxidative properties of flavonoids with respect to the oxidative burst of phagocytes and cooperation between phagocytes and endothelial cells (IAB6004204)

and their metabolites will be characterised chemiluminometrically as a potential to scavenge individual free radicals. Functional properties of human professional phagocytes, activation and function of professiona...

ED - Fyziologie

  • 2002 - 2004
    • •
  • 3 395 tis. Kč
    • •
  • 1 609 tis. Kč
    • •
  • AV ČR
Projekt

Melatonin as a novel antioxidant and radical scavenger melatonin levels in berry species (OC 154)

optimalisation of method to evaluate content of melatonin, evaluation of melatonin content in economically important berries...

GF - Choroby, škůdci, plevely a ochrana rostlin

  • 2007 - 2010
    • •
  • 2 769 tis. Kč
    • •
  • 909 tis. Kč
    • •
  • MŠMT
Projekt

Influence of drugs on metal induced oxidative stress (GA307/96/0038)

. The protective effect of various chelators, free radicals scavengers of natural originOxidative tissue damage caused by the increased formation of free radicals represents one of the possible mechanism o...

FR - Farmakologie a lékárnická chemie

  • 1996 - 1998
    • •
  • 960 tis. Kč
    • •
  • 960 tis. Kč
    • •
  • GA ČR
Projekt

Role of exaggerated inflammatory responses in brain damage during bacterial meniningitis and modalities of its modulation (NR8014)

Brain inflammatory injury during bacterial meningitis is caused by neutrophils and macrophages recruited into the CNS releasing proinflammatory cytokines and free oxygen and nitrogen radicals. Activation of intrathecal immu...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2004 - 2006
    • •
  • 4 250 tis. Kč
    • •
  • 4 056 tis. Kč
    • •
  • MZ
Projekt

The study of the role of free radicals in regulation of senescence in plants (GA522/03/0312)

The study of the role of free radicals in regulation of senescence in plants theory of ageing is based on the action of free radicals. However, their role is in relation to free radical reactions ...

CE - Biochemie

  • 2003 - 2005
    • •
  • 4 297 tis. Kč
    • •
  • 2 304 tis. Kč
    • •
  • GA ČR
Projekt

Mechanisms and consequences of brain damage associated with seizure activity in immature rats (GA309/02/1238)

glutamatereceptor subtype selective agonists and/or antagonists and free radical scavengers associated with seizure activity and to elucidate conditions leading to neuroprotection),both in the regions with marked ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2002 - 2004
    • •
  • 7 582 tis. Kč
    • •
  • 3 072 tis. Kč
    • •
  • GA ČR
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