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3 878 (0,079s) •

Projekt

Differential diagnostics of inflammatory and autoimmune CNS diseases by means of CSF protein fractions evaluation. (NF6460)

The project follows preceding works of our working group and assumes the evaluation of biological significance of CSF protein fractions by means of analytical methods, by monitoring CSF cytological picture and employment of...

FH - Neurologie, neurochirurgie, neurovědy

  • 2001 - 2003
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  • 1 069 tis. Kč
    • •
  • 990 tis. Kč
    • •
  • MZ
Projekt

Investigation of cerebrospinal fluid in diagnostics of inborn errors of neurotransmitter metabolism and mitochondrial diseases. (NS10561)

will be analyses of specific proteins in CSF in patients with mitochondrial disorders. and/or their metabolites in CSF. Central nervous system belongs to the most affected organ also in mitochodriopathies and CSF ...

FG - Pediatrie

  • 2009 - 2011
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  • 4 599 tis. Kč
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  • 4 599 tis. Kč
    • •
  • MZ
Projekt

Cytokinin and acute phase proteins in laboratory diagnosis and prognosis of human ovarian cancer. (IZ2258)

9F - 9

  • 1994 - 1996
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  • 212 tis. Kč
    • •
  • 424 tis. Kč
    • •
  • MZ
Projekt

Enhancement of G-CSF action by adenosine signalling testing of its potential clinical use in murine models (GA306/99/0027)

effects of granulocyte colony-stimulating factor (G-CSF) and drugs elevating with respect to the clinical use of G-CSF. Interactions of G-CSF with dipyridamole and AMP will be studied in the following two experimental situ...

ED - Fyziologie

  • 1999 - 2001
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  • 2 397 tis. Kč
    • •
  • 1 821 tis. Kč
    • •
  • GA ČR
Projekt

Validation of specific mitophagy biomarkers across Alzheimer's disease continuum (TO01000215)

to: 1.)Determine changes of designated mitophagy proteins in serum and CSF of AD (CSF) in participants from the Czech Brain Aging Study (CBAS).This Czech–Norwegian proteins as early diagnostic marker of AD.......

Clinical neurology

  • 2021 - 2024
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  • 33 013 tis. Kč
    • •
  • 23 548 tis. Kč
    • •
  • TA ČR
Projekt

Combined therapy of minimal residual disease using IL-2 and GM-CSF as recombinant cytokines or genetically modified vaccines (NC5526)

The grant project is aimed at a combined therapy of tumours using IL-2 and GM-CSF as recombinant cytokines or genetically modified tumour vaccines.......

FD - Onkologie a hematologie

  • 1999 - 2001
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  • 2 856 tis. Kč
    • •
  • 2 566 tis. Kč
    • •
  • MZ
Projekt

The role of signalling through adenosine receptors and its interaction with G-CSF in regulation of haematopoiesis (GP305/03/D050)

in the frame of the garant's project, and investigation of its interaction with G-CSF alone or in combination with G-CSF will be performed. Besides the nonspecific of selected haematopoietic growth factors, namely GM-CSF, ...

FR - Farmakologie a lékárnická chemie

  • 2003 - 2006
    • •
  • 677 tis. Kč
    • •
  • 677 tis. Kč
    • •
  • GA ČR
Projekt

Possibilities of the enhancement of G-CSF efficacy under conditions of radiation-induced myelosuppression by the extracellular adenosine receptor action (GA306/96/1721)

of granolocyte colony-stimulating factor (G-CSF). The efficacy of the combined action of mechanism of extracellular adenosine signalling and of the G-CSF willbeevaluated under of the project is to contribute to t enhancement andopt...

BO - Biofyzika

  • 1996 - 1998
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  • 2 017 tis. Kč
    • •
  • 1 423 tis. Kč
    • •
  • GA ČR
Projekt

Utilization of RT-QuIC assay for improvement of diagnostics of neurodegenerative diseases Prospective and retrospective studies (NU23-04-00173)

of specific pathological amyloid forming proteins within the brain tissue. At present is based on assumption that the pathological amyloid forming proteins represent true and aggregate the corresponding native recombinant prote...

Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

  • 2023 - 2026
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  • 13 085 tis. Kč
    • •
  • 13 085 tis. Kč
    • •
  • MZ
Projekt

Free light chains of immunoglobulins in cerebrospinal fluid, serum and urine in multiple sclerosis (GP309/02/D066)

) in cerebrospinalfluid (CSF) in the diagnosis of multiple sclerosis (MS) in a larger series of about in CSF, serum and urine (and, possibly, also the number of fLC bands in CSF) and between a)the results of other CSF

FH - Neurologie, neurochirurgie, neurovědy

  • 2002 - 2005
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  • 72 tis. Kč
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  • 47 tis. Kč
    • •
  • GA ČR
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