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Projekt

Eukaryotic-type regulatory proteins in streptomycetes Roles of WD-40 repeat proteins and protein Ser/Thr kinases (GP204/02/D120)

WD-40 repetitive proteins and protein Ser/Thr kinases represent crucial components of eukaryotic regulatory circuits, though their occurrence in prokaryotes of the project is to characterize two of these WD-40 genes (wdpB a...

EB - Genetika a molekulární biologie

  • 2002 - 2005
    • •
  • 696 tis. Kč
    • •
  • 696 tis. Kč
    • •
  • GA ČR
Projekt

Václav Navrátil (1904-1961), his work and place in Czech culture 1930s and 40s. Reconstruction of the work Art and Metaphysics (GA408/09/2017)

My purpose is to bring closer the work of Václav Navrátil, its interpretation and specification, its place in the context of the Czech culture of the 30s and 40s of the tendencies of the avant-garde in Czech pre-war art, overlooked ...

AL - Umění, architektura, kulturní dědictví

  • 2009 - 2010
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  • 183 tis. Kč
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  • 183 tis. Kč
    • •
  • GA ČR
Projekt

Czech Official Fine Arts in the Period of 1948-1958 (DA99P01OOU011)

with the European art development in general in the 40s of the 20th century. AnunbiasedThe decade of 1948-1958 represents a complicated, not yet reflected and not commented on period in the history of Czech official fine arts

AL - Umění, architektura, kulturní dědictví

  • 1999 - 2001
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  • 186 tis. Kč
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  • 185 tis. Kč
    • •
  • MK
Projekt

Relationship between activity of protein Ser/Thr kinases and inter- and intracellular signalling in differentiating and pathogenical bacterial species (GA204/02/1423)

Transmission of a signal by protein phosphorylation at serine, threonine and tyrosine residues plays a major role in differentiation and cell-to-cell communication in eukaryotes. To date, protein Ser/Thr kinases have been shown to be involve...

EB - Genetika a molekulární biologie

  • 2002 - 2004
    • •
  • 5 046 tis. Kč
    • •
  • 3 795 tis. Kč
    • •
  • GA ČR
Projekt

The role of Ser/Thr protein kinase StkP in regulation of cell division in Streptococcus penumoniae (GAP302/12/0256)

The human pathogen Streptococcus pneumoniae is an excellent model to study eukaryotic-like protein kinases in bacteria since its genome only encodes for a single Ser/Thr protein kinase StkP. Prior studies demonstrated that StkP regulates cel...

EE - Mikrobiologie, virologie

  • 2012 - 2016
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  • 7 895 tis. Kč
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  • 7 895 tis. Kč
    • •
  • GA ČR
Projekt

Utilisation of biomass and mixtures for thr gas production (1P05ME746)

cooperation on progress concept of gasification - burning with the purpose of hydrogen production (AGC)...

DD - Geochemie

  • 2005 - 2008
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  • 1 002 tis. Kč
    • •
  • 796 tis. Kč
    • •
  • MŠMT
Projekt

Influence of UHMWPE type of polyethylene on the lifetime of knee replacements and relationship with the implant surfaces design (NU21-06-00084)

employed in the total hip replacements (THR), but recently they are being introduced for THR. The results were published in the form of recommendations, which of the modern UHMWPE types are the most promising from the point of view...

Surgery

  • 2021 - 2024
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  • 8 757 tis. Kč
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  • 8 757 tis. Kč
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  • MZ
Projekt

Role of a novel cytokine IL-40 in the pathogenesis of rheumatoid arthritis (NU21-05-00276)

IL-40 is a novel B-cell associated cytokine involved in the regulation with autoimmunity was suggested. Based on our preliminary results, IL-40 is upregulated) and decreases following B-cell depleting therapy. Moreover, serum IL-

Rheumatology

  • 2021 - 2024
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  • 9 430 tis. Kč
    • •
  • 9 430 tis. Kč
    • •
  • MZ
Projekt

Relationship between the virulence of pathogenic bacteria and the presence of eukaryotic-type Ser/Thr protein kinases (GA204/08/0783)

Signal transduction pathways in both prokaryotes and eukaryotes utilize protein phosphorylation as a key regulatory mechanism. In bacteria, the two-component signal transduction system is predominant. Recent studies have proven that eukaryotic-type s...

EB - Genetika a molekulární biologie

  • 2008 - 2010
    • •
  • 3 834 tis. Kč
    • •
  • 3 834 tis. Kč
    • •
  • GA ČR
Projekt

Elucidation of Haspin kinase interactome and its role in the context of cell plasticity (GA23-06472S)

Cell cycle progression is closely linked to self-renewal, plasticity and cell fate decision making, allowing tissue specification, regeneration, and homeostasis. Haspin is an atypical Ser/Thr kinase with a well-described function in normal m...

Cell biology

  • 2023 - 2025
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  • 8 615 tis. Kč
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  • 8 615 tis. Kč
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  • GA ČR
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