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10 938 (0,103s)

Výsledek výzkumu

Design, Synthesis, and Evaluation of Probes for Spatially Resolved Imaging of Enantioselective Sulfoxide Reductases

A novel concept of nonhydrolytic enzyme sensing based on aggregation-induced emission is described. As a proof of principle, fluorogenic probes for methionine sulfoxide reductases have been developed. Changes in the polarity and ele...

Organic chemistry

  • 2022
  • Jimp
  • Odkaz
Výsledek výzkumu

A Systematic Study of Coumarin-Tetrazine Light-Up Probes for Bioorthogonal Fluorescence Imaging

Fluorescent probes that light-up upon reaction with complementary bioorthogonal reagents are superior tools for no-wash fluorogenic bioimaging applications coumarin-tetrazine probes that produce fluorescent dyes with except...

Organic chemistry

  • 2020
  • Jimp
  • Odkaz
Výsledek výzkumu

Organosulfur/selenium-based Highly Fluorogenic Molecular Probes for Live-Cell Nucleolus Imaging

We present fluorogenic cationic organo chalcogens that are highly selective red-emissive probes bearing a favorable cyclic sidearm for selective and high contrast imaging of cell nucleoli. The probes exhibit high quantum yi...

Biochemistry and molecular biology

  • 2022
  • Jimp
  • Odkaz
Výsledek výzkumu

(-)-CHANA, a fluorogenic probe for detecting amyloid binding alcohol dehydrogenase HSD10 activity in living cells

this significant shortcoming, we have developed a novel fluorogenic probe, (-)-cyclohexenyl. Herein, we define the parameters under which this probe can be......

FR - Farmakologie a lékárnická chemie

  • 2010
  • Jx
Výsledek výzkumu

Bioorthogonal Fluorescence Turn-On Labeling Based on Bicyclononyne-Tetrazine Cycloaddition Reactions that Form Pyridazine Products

Fluorogenic bioorthogonal reactions enable visualization of biomolecules with excellent signal-to-noise ratio. A bicyclononyne-tetrazine ligation that produces fluorescent pyridazine products has been developed. In stark contrast to previous...

Organic chemistry

  • 2019
  • Jimp
  • Odkaz
Výsledek výzkumu

Design and Synthesis of Aza-Bicyclononene Dienophiles for Rapid Fluorogenic Ligations

Fluorogenic bioorthogonal reactions enable visualization of biomolecules under native conditions with excellent signal-to-noise ratio. Here, we present the design and synthesis of conformationally-strained aziridine-fused trans-cyclooctene (...

Organic chemistry

  • 2018
  • Jimp
  • Odkaz
Výsledek výzkumu

Direct fluorogenic detection of palladium and platinum organometallic complexes with proteins and nucleic acids in polyacrylamide gels

Allyl- and propargyl ethers of umbelliferone are sensitive probes for palladium and platinum, including anticancer compounds cisplatin, carboplatin and oxaliplatin, and effective for direct visualization of protein and DNA complexes with org...

Analytical chemistry

  • 2020
  • Jimp
  • Odkaz
Výsledek výzkumu

Excited-State Dynamics of Fluorogenic Molecules

Fluorogenic molecules have attracted a significant share of both academic of the fluorogenic molecules necessitates an in-depth understanding and manoeuvring of fluorogenic behaviour is discussed. Applications of fluoro...

Physical chemistry

  • 2019
  • D
  • Odkaz
Výsledek výzkumu

Synthesis of C3-Substituted N1-tert-Butyl 1,2,4-Triazinium Salts via the Liebeskind–Srogl Reaction for Fluorogenic Labeling of Live Cells

) substituent, yields a fluorogenic triazinium probes suitable for no-wash, live-cell...

Organic chemistry

  • 2024
  • Jimp
  • Odkaz
Výsledek výzkumu

Detection of Escherichia coli and enterococci by means of fluorogenic substrates

Indicators E.coli and intestinal enterocci were detected by means of miniaturized methods (microplates from the Biorad company) according to international standards EN ISO 9308-3 and EN ISO 7899-1, using fluorogenic substrates. It was found ...

DJ - Znečištění a kontrola vody

  • 2002
  • D
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