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Projekt

Predictive and prognostic factors in esophageal cancer patients treated with combined modality therapy protocol-preoperative chemoradiotherapy and surgical resection (NC7530)

Neoadjuvant chemoradiation and consecutive surgery of patients with esophageal cancor may prolong survival. Nutritional deficit present in substantial part o patients may lead to treatment failure. Purpose of this study to evaluate efficacy of intens...

FD - Onkologie a hematologie

  • 2003 - 2005
  • 2 027 tis. Kč
  • 1 982 tis. Kč
  • MZ
Projekt

Sequential FDG-PET and plasma and tissue miRNA as a biomarker of preoperative treatment strategy in locally advanced oesophagogastric cancer (NV17-29389A)

The primary objective is a clinical evaluation exploring the value of PET as a predictor of early histopatological response to preoperative chemotherapy in patients esophagogastric cancer. The prognostically unfavorable patient not respondin...

FD - Onkologie a hematologie

  • 2017 - 2021
  • 13 312 tis. Kč
  • 13 175 tis. Kč
  • MZ
Projekt

The research of interactions between metabolism of fluorinated pyrimidines and ionizing radiation, influence on prediction of chemoradiotherapy effects (NC7372)

The project is aimed to create and verifity a set of predictors for chemoradiotherapy with fluorinated pyrimidines 5-FU, capecitabine and gemcitabine. It is based on known predictors - pyrimidines metabolising enzymes. The project examines c...

FD - Onkologie a hematologie

  • 2003 - 2004
  • 1 055 tis. Kč
  • 1 009 tis. Kč
  • MZ
Projekt

The influences of standard preoperative starvation and thirst on general patients´ conditions. (NR8037)

A prospective clinical trial of influence of preoperative preparation on the patient´s conditions according to a method of preparation: preoperative thirst and starvation or application of fluids and artificial nutrition perorally o...

FJ - Chirurgie včetně transplantologie

  • 2004 - 2008
  • 3 278 tis. Kč
  • 3 187 tis. Kč
  • MZ
Projekt

The risk factors of the liver and bile ducts injury in the preoperative period of the donor (ND6607)

In the preoperative period, there are a number of risk factors which may cause infury to donor organs. The aim to establish - using bile analysis and bile duct histochemistry - the impact of these factors on the quality of the liver and bile...

FJ - Chirurgie včetně transplantologie

  • 2001 - 2003
  • 1 630 tis. Kč
  • 1 564 tis. Kč
  • MZ
Projekt

Use of Magnetic Resonance in the Assessment of Indications for Upper Urinary Tract obstruction Surgeries in Children (NE7105)

The use of magnetic resonance for preoperative examination of the pelvicaliceal system of the kidney and ureters seems to be a welcome alternative to currently used techniques. The speed of the new techniques makes it also less expensive. St...

FG - Pediatrie

  • 2002 - 2003
  • 723 tis. Kč
  • 711 tis. Kč
  • MZ
Projekt

The effect of the preoperative period on the bile ducts injury of the cadaveric donor liver graft (NR8108)

A number of risk factors is present in the preoperative period of cadaveric donor. The goal is to determine, using immunohistochemical testing of the bile ducts, the effect of these factors on the quality of the donor organ. The second goal ...

FJ - Chirurgie včetně transplantologie

  • 2004 - 2006
  • 2 747 tis. Kč
  • 2 646 tis. Kč
  • MZ
Projekt

Preoperative portal vein embolization using PHEMA as an embolizing agent in patients scheduled to extensive hepatectomy (NT11273)

To establish whether the substance referred to as PHEMA, produced/developed by the the Institute of Macromolecular Chemistry, Czech Academy of Sciences, is a material suitable for preoperative embolization of the portal vein vessel bed. Port...

FD - Onkologie a hematologie

  • 2010 - 2014
  • 4 984 tis. Kč
  • 4 884 tis. Kč
  • MZ
Projekt

Analysis of preoperative /perioperative impacts and longitudinal evalution of indices of funcional abnormalities devalopment after repair of congenital heart defects. Permanent lung remodeling? (NE7641)

preoperative pulmonary hemodynamics itself. Perioperative impacts are rather irrelevant. Corrective heart surgery do not impair but surprisingly do not improve preoperative lung is focused on analysis of preoperative/perio...

FF - ORL, oftalmologie, stomatologie

  • 2003 - 2005
  • 1 806 tis. Kč
  • 1 801 tis. Kč
  • MZ
Projekt

Preoperative Regional Chemotherapy in Colon Cancer Patients (NS9690)

This study focuses on the preoperative hepatic and regional arterial chemotherapy in patients with the large bowel carcinoma in the stages II or III. This kind of treatment should prolong the overall survival interval and prevent the uprisin...

FJ - Chirurgie včetně transplantologie

  • 2008 - 2011
  • 3 304 tis. Kč
  • 3 135 tis. Kč
  • MZ
  • 1 - 10 z 56