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9 955 (0,069s) •

Projekt

Effect of glutamate in vitro on the high-affinity choline uptake and lipid peroxidation in brain tissue. (IZ1805)

9F - 9

  • 1994 - 1995
    • •
  • 110 tis. Kč
    • •
  • 220 tis. Kč
    • •
  • MZ
Projekt

Regulation of the high-affinity choline uptake during pathologic conditions and ontogenetic development (IZ3702)

FL - Psychiatrie, sexuologie

  • 1996 - 1997
    • •
  • 587 tis. Kč
    • •
  • 587 tis. Kč
    • •
  • MZ
Projekt

Comparison of effects of amyloid beta peptide 1-40 and 1-42 on hemicholinium-3 sensitive choline carriers and influence of cholesterol (GA305/03/1547)

and associatedwithhigh-affinity choline transport and acetylcholine synthesis. It is not fully clear demonstrated effects of nonaggregated Abeta 1-40 on hemicholinium-3 sensitive choline......

FH - Neurologie, neurochirurgie, neurovědy

  • 2003 - 2005
    • •
  • 1 404 tis. Kč
    • •
  • 1 404 tis. Kč
    • •
  • GA ČR
Projekt

Influence of oxidative stress on cholinergic neurones and ways of their protection (IAA5011206)

The objective is to enhance the understanding of molecular events responsible for impairments of neural functions in old age and Alzheimer's disease (AD). Memory impairments in normal aging and AD depend on the deterioration of cholinergic functions....

FH - Neurologie, neurochirurgie, neurovědy

  • 2002 - 2006
    • •
  • 7 464 tis. Kč
    • •
  • 4 755 tis. Kč
    • •
  • AV ČR
Projekt

Changes in composition of neuronal membranes and in the regulation of choline transport in brain tissue of patients with senile dementia (PG96185)

9F - 9

  • 1996 - 1996
    • •
  • 0 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MŠMT
Projekt

Trk1 potassium importers - key transport systems for yeast cell fitness and multiple-stress tolerance (GA20-04420S)

plasma-membrane potential and intracellular pH. The Trk transporters of some non-conventional yeasts should have a very high transport capacity and affinity to ensure eukaryotes which is supposed to be able to qui...

Microbiology

  • 2020 - 2023
    • •
  • 4 993 tis. Kč
    • •
  • 4 993 tis. Kč
    • •
  • GA ČR
Projekt

The use of affinity chromatography for identification of sterol-binding proteins from plants (IAA4055204)

and which affinity. Data will serve for optimization of steroid structures to prepare high-affinity binding matrices for plant PBPs, their isolation and study. questions about the mode of steroid-binding and transport<...

CC - Organická chemie

  • 2002 - 2006
    • •
  • 4 941 tis. Kč
    • •
  • 2 661 tis. Kč
    • •
  • AV ČR
Projekt

Molecular mechanism of interaction between the H4-H5 loop of Na+/K+-ATPase and the binding site for cardiac glycosides (IAA7011801)

. These binding sites, however, apparently cooperate. As revealed recently, the high (E1) and low (E2) affinity ATP binding sites coexist at the functional Na+/K+ complex. There is not clear, yet, whether one binding site has differ...

BO - Biofyzika

  • 1998 - 2000
    • •
  • 1 852 tis. Kč
    • •
  • 1 075 tis. Kč
    • •
  • AV ČR
Projekt

Investigation on the role of cholinergic neurotransmission in aging and pathogenesis of Alzheimer´s disease (IAA500110703)

Alzheimer´s disease (AD) is the most common neurodegenerative disease and represents a major health problem in developed countries. The primary event in its pathogenesis is increased production of beta-amyloid. Noxious species of beta-amyloid are sol...

ED - Fyziologie

  • 2007 - 2011
    • •
  • 7 060 tis. Kč
    • •
  • 7 060 tis. Kč
    • •
  • AV ČR
Projekt

Influence of the nerve agent and reactivators of Acetyl Choline Esterase on the Guinea Pig (OVUOFVZ200905)

The aim of this project is determine the physiological activity of Acetyl Choline Esterase (AChE) and detection of LD50 of inhibitors paraoxon, tabun, cyklosarine and reactivators AChE pralidoxim, obidoxim, trimedoxim, HI-6, methoxim. Next t...

FP - Ostatní lékařské obory

  • 2009 - 2011
    • •
  • 2 384 tis. Kč
    • •
  • 894 tis. Kč
    • •
  • MO
  • 1 - 10 z 9 955