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1 161 (0,089s)

Projekt

Pathophysiology of Acute Lung Injury and Factors Determining the Course of Recovery (GA305/93/2395)

ED - Fyziologie

  • 1993 - 1995
  • 275 tis. Kč
  • 550 tis. Kč
  • GA ČR
Projekt

Increased extravascular lung water and impaired gut integrity in the acute respiratory distress syndrome as a part of systemic inflammatory syndrome (ND5649)

To investigate pathophysiology of abnormal accumulation of extravascular lung water (EVLW) in acute respiratory distress syndrome and to evaluate a relationship between pulmonary vascular injury and intestinal permeability....

FJ - Chirurgie včetně transplantologie

  • 1999 - 2001
  • 2 578 tis. Kč
  • 2 536 tis. Kč
  • MZ
Projekt

Studies on acute stimulation and desquamation of the pulmonary vascular endothelium in isolated perfused rat lungs (GA306/99/0649)

Acute stimulation of the pulmonary endothelium in acute lung injury caused by various stimuli leads to the release of different mediators and soluble endothelial is to study "ex vivo" acute endothelial sti...

ED - Fyziologie

  • 1999 - 2000
  • 460 tis. Kč
  • 460 tis. Kč
  • GA ČR
Projekt

Noninvasive assessment of oxidative stress in the preterm newborns by an analysis of exhaled (GA305/01/0794)

Reactive oxygen species (ROS) have been implicated in the pathogenesis of acute as well as chronic lung injury in premature new-borns. It is believed that increased concentration of oxygen used during ventilatory support pa...

FG - Pediatrie

  • 2001 - 2003
  • 2 691 tis. Kč
  • 2 456 tis. Kč
  • GA ČR
Projekt

Role of free radicals in the regulation of lung inflammation induced by acute and chronic exposure to endotoxin (GA524/06/1197)

dust induced chronic lung inflammations. Reactive oxygen and nitrogen species (RONS injury, in the mechanism of LPS mediated toxicity. Significant sources of RONS and other pro-inflammatory mediators in the inflamed lungs ...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2006 - 2008
  • 3 101 tis. Kč
  • 3 101 tis. Kč
  • GA ČR
Projekt

Influence of pulmonary contusion on the prognosis of children with serious injury. Effect of the mechanical ventilation. (ND5869)

Analysis of a group of children with thoracic injury in a period of 10 years aimed at duration and mode of mechanical ventilation. Analysis of a group of children after prolonged mechanical ventilation without thoracic injury in a 1...

FJ - Chirurgie včetně transplantologie

  • 2000 - 2002
  • 1 354 tis. Kč
  • 1 354 tis. Kč
  • MZ
Projekt

Mechanisms of early and late changes of pulmonary blood vessels after the lung tissue injury (GA305/96/0068)

ED - Fyziologie

  • 1996 - 1996
  • 0 tis. Kč
  • 2 055 tis. Kč
  • GA ČR
Projekt

Ischaemia reperfusion injury in accute myocardial infarction (NT13709)

Myocardial injury at acute myocardial infarction is in up to 50% caused by reperfusion and excessive release of free oxygen radicals. Direct measurement of free with comet assay, can establish reperfusion injury. Measuremen...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2012 - 2014
  • 2 778 tis. Kč
  • 2 778 tis. Kč
  • MZ
Projekt

Ischemia-reperfusion injury of lungs retrieved from non-heart-beating donors, protection of radical damage (GPP303/10/P343)

Non-heart-beating donors (NHBD)  transplantation technique, using lungs the scarcity of suitable organ donors. The most important factor for the lung viability the experimental model of lung retrieval from NHBD, in previous...

ED - Fyziologie

  • 2010 - 2012
  • 1 174 tis. Kč
  • 1 174 tis. Kč
  • GA ČR
Projekt

Unlocking the potential of stable FGF10 for lung regeneration in patients with Acute Respiratory Distress Syndrome (ARDS) (TQ13000027)

We aim to develop a new pharmacological treatment based on our patented molekule FGF10-STAB for patients suffering from acute respiratory distress syndrome (ARDS) for which there is no treatment available. Specific objectives for the TACR pr...

Health-related biotechnology

  • 2024 - 2024
  • 700 tis. Kč
  • 490 tis. Kč
  • TA ČR
  • 1 - 10 z 1 161