Vše

Co hledáte?

Vše
Projekty
Výsledky výzkumu
Subjekty

Rychlé hledání

  • Projekty podpořené TA ČR
  • Významné projekty
  • Projekty s nejvyšší státní podporou
  • Aktuálně běžící projekty

Chytré vyhledávání

  • Takto najdu konkrétní +slovo
  • Takto z výsledků -slovo zcela vynechám
  • “Takto můžu najít celou frázi”
CS
ČeštinaEnglish

Filtry

3 122 (0,08s) •

Projekt

Detection of mutations in the GDAP1, LITAF, PRX and NEFL genes as newly discovered possible causes of inherited neuropaties Charcot-Marie-Tooth - extended investigation in the large cohort (1A8254)

candidate genes - mainly LITAF, GDAP1, PRX and NEFL in a large previously collected excluded main mutations - CMT1A duplication/ HNPP deletion, Cx32, MPZ and PMP22 gene mutations.......

FH - Neurologie, neurochirurgie, neurovědy

  • 2004 - 2006
    • •
  • 2 686 tis. Kč
    • •
  • 2 661 tis. Kč
    • •
  • MZ
Projekt

Analysis of plant gene regulation systems by constitutive gene activation (GA204/97/0154)

The basis of this project proposal is T-DNA gene tagging of Arabidopsis thaliana by constitutive gene activation with the use of 35S promotor. It is planned will beused. Three types of mutations will be scored in the offspr...

EB - Genetika a molekulární biologie

  • 1997 - 1999
    • •
  • 4 900 tis. Kč
    • •
  • 3 042 tis. Kč
    • •
  • GA ČR
Projekt

Detection of mutation in MLH1, MSH2 and APC genes in the sporadic colorectal adenomas (NK7270)

Immunohistochemistry is a new method for detection of the loss of expression of MLH1, MSH2 and APC genes. The aim of the study is to determine the frequency of mutations in the genes mentioned above in soradic colorectal ad...

FE - Ostatní obory vnitřního lékařství

  • 2002 - 2004
    • •
  • 1 445 tis. Kč
    • •
  • 1 426 tis. Kč
    • •
  • MZ
Projekt

Prevalence of known mutations and search for new gene mutations and polymorphisms in patients with MODY diabetes in the Czech Republic. (NB6122)

Known mutations will be estimated and new mutations and polymorphisms will be searched in 5 genes responsible for MODY diabetes by direct gene sequencing. Consequently, genotype-phenotype correlation based on clini...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2000 - 2002
    • •
  • 2 615 tis. Kč
    • •
  • 2 613 tis. Kč
    • •
  • MZ
Projekt

Screening of mutations in the PKD2 gene from families with autosomal dominant polycystic kidney disease. (NE5996)

Analysis of mutations in PKD2 gene in selected families with ADPKD by screening methods (SSCP,HA,DGGE) and following sequenation of positive fragments. Analysis of mutations in PKD2 gene is the only temporary avail...

FE - Ostatní obory vnitřního lékařství

  • 2000 - 2002
    • •
  • 3 422 tis. Kč
    • •
  • 3 420 tis. Kč
    • •
  • MZ
Projekt

Role of dominant susceptibility genes in breast tumorigenesis - RNA-based analyses (NR9051)

The role of missense variants in BRCA1 and BRCA2 genes will be analyzed in brest cancer tumorigenesis. BRCA1 a BRCA2 genes will be screened for rearrangements and splice variants. Mutational analysis of ATM gene wi...

FD - Onkologie a hematologie

  • 2006 - 2008
    • •
  • 2 936 tis. Kč
    • •
  • 2 808 tis. Kč
    • •
  • MZ
Projekt

Mutational status of IgVH genes in chronic lymphocytic leukemia (NM7604)

Introducing examination of the mutational status of IgVH genes will help the clinicians in therapeutic decision in patients with CLL. The results of the mutational status of IgVH genes and their prognostic signific...

EB - Genetika a molekulární biologie

  • 2003 - 2005
    • •
  • 1 885 tis. Kč
    • •
  • 1 798 tis. Kč
    • •
  • MZ
Projekt

Molecular analysis of the APC and MYH genes in families affected with familial adenomatous polyposis or multiple adenomas (NR8103)

DNA diagnosis, frequence and type of germline mutations, MYH gene and colorectalGenetic causes of FAP, AFAP and multiple adenomas in the selected set of families with no demonstrable germline APC mutation. Analysis of invi...

FD - Onkologie a hematologie

  • 2004 - 2006
    • •
  • 2 846 tis. Kč
    • •
  • 2 810 tis. Kč
    • •
  • MZ
Projekt

HEREDITARY BREAST AND OVARIAN CANCER THE ROLE OF LOW PENETRANCE GENES IN TUMORIGENESIS (NS10304)

tested negatively for major susceptibility genes (BRCA1/2) Mutation analysis of low in BRCA1 and BRCA2 genes. To analyze the impact of identified mutations on breast penetrance genes will be also examined...

FD - Onkologie a hematologie

  • 2009 - 2011
    • •
  • 5 456 tis. Kč
    • •
  • 5 456 tis. Kč
    • •
  • MZ
Projekt

Germline mutations of PML gene in patients with cancer (NR9092)

Mutational analysis of PML gene will be performed in patients with breast and colon cancer with suspect hereditary predisposition to cancer. Cyclin D1 and ZNF217 gene amplification analysis will be performed in breast cance...

FD - Onkologie a hematologie

  • 2006 - 2008
    • •
  • 2 645 tis. Kč
    • •
  • 2 244 tis. Kč
    • •
  • MZ
  • 1 - 10 z 3 122