Stochastic Prediction of Arterial Wall rupture
Public support
Provider
Czech Science Foundation
Programme
Standard projects
Call for proposals
SGA0202600001
Main participants
Vysoká škola báňská - Technická univerzita Ostrava / Fakulta strojní
Contest type
VS - Public tender
Contract ID
26-21225S
Alternative language
Project name in Czech
Stochastic Prediction of Arterial Wall rupture
Annotation in Czech
Cardiovascular diseases are the leading cause of death in the Western world. Reliable biomechanical rupture risk assessment (BRRA) of abdominal aortic aneurysms (AAA) requires accurate constitutive models and geometry. Current models often assume incompressibility and rely on uniaxial data, neglecting biaxial stress states and cyclic loading. We propose a new experimental framework combining radial compression with existing methods to better capture arterial behavior and improve rupture prediction. A validated stochastic model will be developed using a Bayesian machine learning approach and validated on both ex-vivo rupture tests of brachial aneurysms (BAA) and an extended database of AAAs with known outcomes. A key innovation is a novel geometry reconstruction algorithm enabling automated modeling of rare pathologies, currently beyond the reach of neural networks due to limited data. This breakthrough could significantly advance patient-specific BRRA and open new clinical applications.
Scientific branches
R&D category
ZV - Basic research
OECD FORD - main branch
10610 - Biophysics
OECD FORD - secondary branch
20302 - Applied mechanics
OECD FORD - another secondary branch
10103 - Statistics and probability
CEP - equivalent branches <br>(according to the <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">converter</a>)
BB - Applied statistics, operational research<br>BO - Biophysics<br>GB - Agricultural machines and construction<br>JQ - Machinery and tools
Solution timeline
Realization period - beginning
Jan 1, 2026
Realization period - end
Dec 31, 2028
Project status
Z - Beginning multi-year project
Latest support payment
—
Data delivery to CEP
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data delivery code
CEP26-GA0-GA-R
Data delivery date
Jun 24, 2026
Finance
Total approved costs
9,348 thou. CZK
Public financial support
9,348 thou. CZK
Other public sources
0 thou. CZK
Non public and foreign sources
0 thou. CZK