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54 (0,157s) •

Project

Study of RNA Editing in Transcripts from Maxicircle Kinetoplast DNA of Trypanosoma Carassii, Trypanosoma Boissoni and Bodo Caudatus (Kinetoplastida). (GA204/94/0285)

EE - Mikrobiologie, virologie

  • 1994 - 1996
    • •
  • 300 tis. Kč
    • •
  • 450 tis. Kč
    • •
  • GA ČR
Project

Recognition factors of Triatoma infestants and their involvement in interactions with Trypanosoma rangeli (GA204/95/0271)

EG - Zoologie

  • 1995 - 1997
    • •
  • 414 tis. Kč
    • •
  • 414 tis. Kč
    • •
  • GA ČR
Project

Recognition factors of Triatoma infestans and their involvement in interactions with Trypanosoma rangeli (IAA6022504)

EG - Zoologie

  • 1995 - 1997
    • •
  • 666 tis. Kč
    • •
  • 666 tis. Kč
    • •
  • AV ČR
Project

Structure characterization of g-RNA from Trypanosoma brucei (1K04011)

In this grant application we propose structural studies of g-RNA molecules that plays essential role in pre-mRNA editing in Kinetoplastida.UV, CD and NMR spectroscopy will be used to charakterize secondary and terciary structures of several g-RNAs fr...

BO - Biofyzika

  • 2004 - 2006
    • •
  • 2 507 tis. Kč
    • •
  • 1 843 tis. Kč
    • •
  • MŠMT
Project

Mitoribosome in Trypanosoma brucei biogenesis and unique traits of a divergent protein synthesis machine (GJ20-04150Y)

Mitoribosomes in Trypanosoma brucei diverged considerably in adaptation to multiple peculiarities of kinetoplastid mitochondrial gene expression, as we and others recently documented by cryoEM. Besides the mature small and large subunit (SSU...

Biochemistry and molecular biology

  • 2020 - 2023
    • •
  • 6 855 tis. Kč
    • •
  • 6 855 tis. Kč
    • •
  • GA ČR
Project

Functional analysis of mitochondrial proteins in Trypanosoma brucei (GA204/06/1558)

Trypanosoma brucei and related kinetoplastid flagellates are early-branching protozoans responsible for serious diseases of man and animals. Their single cell, and in particular their mitochondrion, contain many unique features. We propose t...

EB - Genetika a molekulární biologie

  • 2006 - 2008
    • •
  • 2 770 tis. Kč
    • •
  • 2 770 tis. Kč
    • •
  • GA ČR
Project

Functional analysis of candidate components of the RNA editing machinery in the flagellate Trypanosoma brucei (IAA5022302)

Trypanosoma brucei is thecausative agent of serious diseases of man and animals. In the mitochondrion of this primitive flagellate, mRNAs undergo extensive editing. Several proteins that participate in this process do not have homologs in hi...

EB - Genetika a molekulární biologie

  • 2003 - 2005
    • •
  • 2 248 tis. Kč
    • •
  • 1 838 tis. Kč
    • •
  • AV ČR
Project

Posttranscriptional modifications of tRNAs in Trypanosoma brucei (LH12104)

One of the striking features of tRNAs is their numerous post-transcriptional modifications. A large number of enzymes required for different modifications have now been identified in many model organisms, but despite some progress little is known abo...

EB - Genetika a molekulární biologie

  • 2012 - 2015
    • •
  • 3 988 tis. Kč
    • •
  • 3 648 tis. Kč
    • •
  • MŠMT
Project

Role of mitochondrial ROS signals in the development of the unicellular parasite Trypanosoma brucei (GA22-34480S)

, the unicellular parasite Trypanosoma brucei, to define mROS-driven cellular differentiation...

Cell biology

  • 2022 - 2022
    • •
  • 3 049 tis. Kč
    • •
  • 3 049 tis. Kč
    • •
  • GA ČR
Project

Queuosine The role of an essential tRNA modification in parasitic protist Trypanosoma brucei (GJ15-21450Y)

, Trypanosoma brucei being our first choice. This is further justified by the fact...

EB - Genetika a molekulární biologie

  • 2015 - 2017
    • •
  • 4 935 tis. Kč
    • •
  • 4 935 tis. Kč
    • •
  • GA ČR
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