Heart transplantation in a highly sensitised patient
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023001%3A_____%2F11%3A00002451" target="_blank" >RIV/00023001:_____/11:00002451 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Heart transplantation in a highly sensitised patient
Original language description
Some patients awaiting heart transplantation may develop positive panel reactive antibodies (PRA). Several reports have demonstrated that pre-transplant sensitisation is associated with decreased survival and a higher rejection rate, and leads to the development of cardiac allograft vasculopathy. We describe our experience with a highly sensitised transplant recipient. To reduce sensitisation, three courses of immunoadsorption were administered. The PRA level decreased effectively and actual cross-matchwas negative. The patient underwent successful heart transplantation, and desensitisation treatment continued with immunoadsorption and intravenous immunoglobulin for five courses. Graft function remains normal at 12 months post-operatively and the clinical status of the patient is stable. Key words: allograft rejection, allograft vasculopathy, immunoadsorption,
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
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Continuities
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Kardiologia Polska
ISSN
0022-9032
e-ISSN
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Volume of the periodical
69
Issue of the periodical within the volume
1
Country of publishing house
PL - POLAND
Number of pages
3
Pages from-to
51-53
UT code for WoS article
000295897800009
EID of the result in the Scopus database
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