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The effect of 5-aminolevulinic acid-based photodynamic treatment (PDT) on nucleoli of leukemic granulocytic precursors represented by K562 blastic cells in vitro.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F04%3AI0000093" target="_blank" >RIV/00023736:_____/04:I0000093 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The effect of 5-aminolevulinic acid-based photodynamic treatment (PDT) on nucleoli of leukemic granulocytic precursors represented by K562 blastic cells in vitro.

  • Original language description

    In contrast to HL60 cells, PDT did not induce apoptosis in K562 cells. PDT produced only necrotic changes in some K562 cells which were expressed by nuclear and cell swelling. Thus, induction of apoptosis, nuclear and nucleolar changes in individual cells do not depend on the inducer, PDT, but on the cell properties.

  • Czech name

    Vliv fotodynamického ošetření (PDT) na nukleolární změny u leukemických buněk K562.

  • Czech description

    Fotodynamické ošetření (PDT) CML buněk K562 nevyvolalo apoptózu, na rozdíl od buněk HL60, ale pouze nekrotické změny projevující se jako nukleární a buněčné bobtnání. Indukce apoptózy a jí provázející nukleární a nukleolární změny tudíž nezávisejí na induktoru - PDT- ale na vlastnostech buněk.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2004

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Medical Science Monitor : International Medical Journal of Experimental and Clinical Research

  • ISSN

    1234-1010

  • e-ISSN

  • Volume of the periodical

    10

  • Issue of the periodical within the volume

    11

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    5

  • Pages from-to

    "BR405"-"BR409"

  • UT code for WoS article

  • EID of the result in the Scopus database