Myelodysplastic syndromes and acute myeloid leukemia with mutations of the tumor suppressor gene TP53

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00023736%3A_____%2F24%3A00013692" target="_blank" >RIV/00023736:_____/24:00013692 - isvavai.cz</a>

Result on the web

<a href="https://novapublishers.com/shop/advances-in-genetics-research-volume-22/" target="_blank" >https://novapublishers.com/shop/advances-in-genetics-research-volume-22/</a>

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Myelodysplastic syndromes and acute myeloid leukemia with mutations of the tumor suppressor gene TP53

Original language description

TP53 gene mutations were detected in 10-20% of patients with de novo myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML). The TP53 mutation is a common molecular abnormality in MDS and is associated with poor outcomes. These outcomes depend on the type of TP53 mutation and variant allele frequency (VAF).

Czech name

—

Czech description

—

Type

C - Chapter in a specialist book

CEP classification

—

OECD FORD branch

30205 - Hematology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Book/collection name

Advances in genetics research: volume 22

ISBN

979-8-89113-693-9

Number of pages of the result

29

Pages from-to

37-65

Number of pages of the book

259

Publisher name

Nova Science

Place of publication

New York

UT code for WoS chapter

—