Effectiveness of Environmentally Safe Food Additives and Food Supplements in an In Vitro Growth Inhibition of Significant Fusarium, Aspergillus and Penicillium species

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027006%3A_____%2F18%3A00004519" target="_blank" >RIV/00027006:_____/18:00004519 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.17221/86/2017-PPS" target="_blank" >http://dx.doi.org/10.17221/86/2017-PPS</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.17221/86/2017-PPS" target="_blank" >10.17221/86/2017-PPS</a>

Result language
angličtina
Original language name
Effectiveness of Environmentally Safe Food Additives and Food Supplements in an In Vitro Growth Inhibition of Significant Fusarium, Aspergillus and Penicillium species
Original language description
We tested 38 legislatively recognised substances such as food additives and supplements for antifungal efficacy, with the aim of providing an alternative to synthetic conventional fungicides. These compounds were tested against 9 significant pathogenic fungal species belonging to the significant genera Fusarium, Penicillium, and Aspergillus. Of these compounds, 6 are proposed as potential candidates to provide a complementary alternative to conventional fungicides. Natamycin provided extreme efficacy expressed as MIC50 (5-31 mu g/ml), followed by BHA and then BHT, CaNa2EDTA, PABA, and chitosan expressed as MIC50 (0.7-1.9 mg/ml). Safety and antifungal activity were discussed in terms of the mode of action and molecular structure, as well as in terms of potential practical use and legislative requirements for the introduction into practice. We presume that food additives and food supplements are definitely a great source of antifungal compounds. In developed areas of the world (e.g. in the EU), they could represent legislatively recognised compounds, so-called basic substances.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
40106 - Agronomy, plant breeding and plant protection; (Agricultural biotechnology to be 4.4)

Project
<a href="/en/project/QJ1610082" target="_blank" >QJ1610082: New possibility of the protection of cereal - basic substances</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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