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EN
ČeštinaEnglish

The roles of c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (p38 MAPK) in aged pig oocytes

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027014%3A_____%2F09%3A%230000989" target="_blank" >RIV/00027014:_____/09:#0000989 - isvavai.cz</a>

  • Alternative codes found

    RIV/60460709:41210/09:31060

  • Result on the web

    —

  • DOI - Digital Object Identifier

    —

Alternative languages

  • Result language

    angličtina

  • Original language name

    The roles of c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (p38 MAPK) in aged pig oocytes

  • Original language description

    After reaching metaphase II, in vitro matured oocytes undergo the complex processes referred to as oocyte aging. Under the culture conditions, some aged oocytes remained at the stage of metaphase II, some underwent spontaneous parthenogenetic activationand others underwent cellular death, either through apoptosis (fragmentation) or lysis. We investigated the effect of c-Jun N-terminal kinases (JNK) and p38 mitogen-activated protein kinase (p38 MAPK) inhibition on pig oocyte aging and the activity of JNK and p38 MAPK during the aging period. Based on our data, we can conclude that JNK plays active role in fragmentation of pig oocytes and that p38 MAPK is not involved in this process.

  • Czech name

    —

  • Czech description

    —

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

    —

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Reproduction and Development

  • ISSN

    0916-8818

  • e-ISSN

    —

  • Volume of the periodical

    55

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    JP - JAPAN

  • Number of pages

    8

  • Pages from-to

    —

  • UT code for WoS article

    000263987700012

  • EID of the result in the Scopus database

    —

Similar results(10)

Inhibition of c-Jun N-terminal kinase (JNK) suppresses porcine oocyte aging in vitroInhibition of c-Jun N-terminal kinase (JNK) suppresses porcine oocyte ageing in vitroSB203580, a pharmacological inhibitor of p38 MAP kinase transduction pathway activates ERK and JNK MAP kinases in primary cultures of human hepatocytes.