Possible genetic damage in the Czech nuclear power plant workers
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F06%3A%230000060" target="_blank" >RIV/00027162:_____/06:#0000060 - isvavai.cz</a>
Alternative codes found
RIV/68378041:_____/06:00041160
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Possible genetic damage in the Czech nuclear power plant workers
Original language description
The aim of our study was to identify occupational risk of irradiation exposure in the Czech nuclear power plant workers. We analyzed levels of chromosomal aberrations, a well known biomarker of early biological effects and a predictor of cancer risk. Wemay conclude that low doses of ionizing radiation to which workers in the Czech nuclear power plants are exposed do not represent by themselves any significant risk of genetic damage as measured by the conventional cytogenetic analysis and FISH. Following factors were identified as potential confounders by the conventional cytogenetic analysis: XPD-6, by the FISH: age, GSTP1 and p53Bst genotypes, long-term use of medication, alcohol consumption, and smoking. No association between the dose of irradiation and the level of chromosomal aberrations in any nuclear power plant was detected either by the conventional cytogenetic analysis or by FISH.
Czech name
Možné genetické poškození pracovníků českých atomových elektráren
Czech description
Cílem studie bylo identifikovat profesionální riziko radiační expozice u pracovníků českých atomových elektráren. Analyzovali jsme frekvenci chromozomálních abnormalit, známé biomárkry časného biologického účinku a márkry rizika rakoviny. Zjistili jsme,že nízké dávky ionizačního záření, kterým jsou zaměstnanci atomových elektráren exponovány, nereprezentují sami o sobě signifikantní riziko poškození, stanovené na základě cytogenetického vyšetření.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/SL%2F5%2F160%2F05" target="_blank" >SL/5/160/05: Environmental factors and health</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2006
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Mutation Research
ISSN
0027-5107
e-ISSN
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Volume of the periodical
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Issue of the periodical within the volume
1-2
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
13
Pages from-to
1-2
UT code for WoS article
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EID of the result in the Scopus database
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