Sub-milliSievert ultralow-dose CT colonography with iterative model reconstruction technique

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F16%3A10325503" target="_blank" >RIV/00064165:_____/16:10325503 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/16:00090665 RIV/00216208:11110/16:10325503 RIV/00159816:_____/16:00065539

Result on the web

<a href="https://peerj.com/articles/1883/" target="_blank" >https://peerj.com/articles/1883/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.7717/peerj.1883" target="_blank" >10.7717/peerj.1883</a>

Result language

angličtina

Original language name

Sub-milliSievert ultralow-dose CT colonography with iterative model reconstruction technique

Original language description

Purpose. The purpose of this study was to evaluate the technical and diagnostic performance of sub-milliSievert ultralow-dose (ULD) CT colonograpy (CTC) in the detection of colonic and extracolonic lesions. Materials and Methods. CTC with standard dose (SD) and ULD acquisitions of 64 matched patients, half of them with colonic findings, were reconstructed with filtered back projection (FBP), hybrid (HIR) and iterative model reconstruction techniques (IMR). Image noise in six colonic segments, in the left psoas muscle and aorta were measured. linage quality of the left adrenal gland and of the colon in the endoscopic and 2D view was rated on a five point Likert scale by two. observers, who also completed the reading of CTC for colonic and extracolonic findings. Results. The mean radiation dose estimate was 4.1 +/- 1.4 mSv for SD and 0.86 +/- 0.17 mSv for ULD for both positions (p < 0.0001). In ULD-IMR, SD-IMR and SD-HIR, the endoluminal noise was decreased in all colonic segments compared to SD FBP (P < 0.001) There were 27 small (6-9 mm) and 17 large (>= 10 mm) colonic lesions that were classified as sessile polyps (n = 38), flat lesions (n = 3), or as a mass (n = 3), Per patient sensitivity and specificity were 0.82 and 0.93 for ULD-FBP, 0.97 and 0.97p for ULD-HIR, 0.97 and 1.0 for ULD-IMR. Per polyp sensitivity was 0.84 for ULD-FBP, 0 98 ULD-HIR, 0.98 for ULD-IMR. Significantly less extracolonic findings were detected in ULD-FBP and ULD-HIR, but in the E4 category by C-BADS (potentially important findings), the detection was similar. Conclusion. Both HIR and IMR are suitable for sub-milliSievert ULD CTC with out sacrificing diagnostic performance of the study.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FP - Other medical fields

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

PeerJ

ISSN

2167-8359

e-ISSN

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Volume of the periodical

4

Issue of the periodical within the volume

March

Country of publishing house

US - UNITED STATES

Number of pages

15

Pages from-to

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UT code for WoS article

000374159800009

EID of the result in the Scopus database

2-s2.0-84963984181