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Catheter Ablation of Ischemic Ventricular Tachycardia With Remote Magnetic Navigation: STOP-VT Multicenter Trial

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064173%3A_____%2F16%3AN0000128" target="_blank" >RIV/00064173:_____/16:N0000128 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11120/16:43911752 RIV/00023884:_____/12:00007146

  • Result on the web

    <a href="http://dx.doi.org/10.1111/jce.12910" target="_blank" >http://dx.doi.org/10.1111/jce.12910</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1111/jce.12910" target="_blank" >10.1111/jce.12910</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Catheter Ablation of Ischemic Ventricular Tachycardia With Remote Magnetic Navigation: STOP-VT Multicenter Trial

  • Original language description

    Study to Obliterate Persistent Ventricular Tachycardia IntroductionCatheter ablation is an effective treatment of scar-related ventricular tachycardia (VT), but the overall complexity of the procedure has precluded its widespread use. Remote magnetic navigation (RMN) has been shown to facilitate cardiac mapping and ablation of VT in a retrospective series. STOP-VT is the first multicenter, prospective, single-arm and single-procedure study evaluating RMN-based mapping and ablation of post-infarction VT. MethodsPatients with documented VT and prior MI, in whom an ICD was implanted either for primary or secondary prevention, were recruited from four EU and US centers. Either a transseptal (48 patients) or transaortic (5 patients) approach was employed to gain access for ventricular endocardial mapping/ablation during VT (entrainment mapping, activation mapping) and/or substrate mapping in sinus rhythm (elimination of fractionated/late potentials, variable extent of substrate modification) with RMN and irrigated RF ablation. The primary endpoints were as follows: (i) non-inducibility of the target VT or any other sustained VT; (ii) elimination of sustained VT/VF during ICD follow-up of up to 12 months. ResultsThe cohort included 53 consecutive patients (median age 67 years, 49 men, median LVEF 31%). One hemodynamically unstable patient was excluded at the onset of mapping. Inducibility of sustained VT was achieved an average of 2.2 times per patient (1-8), with mean tachycardia cycle length (TCL) 374 milliseconds (179-510). Mean total procedure and fluoroscopy times were 223 minutes and 8.7 minutes, respectively; mean cumulative fluoroscopy time during mapping and ablation was 0.95 minutes; maximum power averaged 42.3 W with nominal saline 30 cc/min irrigation; mean cumulative RF time was 38 minutes.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FA - Cardiovascular diseases including cardio-surgery

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    N - Vyzkumna aktivita podporovana z neverejnych zdroju

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Cardiovascular Electrophysiology

  • ISSN

    1045-3873

  • e-ISSN

  • Volume of the periodical

    27

  • Issue of the periodical within the volume

    Suppl. 1

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    9

  • Pages from-to

    S29-S37

  • UT code for WoS article

    000373062000006

  • EID of the result in the Scopus database

    2-s2.0-84960460058