Short-term low-carbohydrate diet decreases body weight and fat mass but not muscle strength in children and young people with type 1 diabetes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064203%3A_____%2F25%3A10500705" target="_blank" >RIV/00064203:_____/25:10500705 - isvavai.cz</a>
Alternative codes found
RIV/60460709:41210/25:103111 RIV/00216208:11130/25:10500705 RIV/00216208:11320/25:10500705
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=~zy3KKUt4Y" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=~zy3KKUt4Y</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41430-025-01658-2" target="_blank" >10.1038/s41430-025-01658-2</a>
Alternative languages
Result language
angličtina
Original language name
Short-term low-carbohydrate diet decreases body weight and fat mass but not muscle strength in children and young people with type 1 diabetes
Original language description
AIMS: We investigated whether a short period of tightly controlled low-carbohydrate diet (LCD) leads to a change in body weight, body composition, and muscle strength in children and young people with diabetes (CYPwD). METHODS: Thirty-five CYPwD were recruited into this randomized controlled cross-over study (20 female; age 14.5 +- 2.9 years). The interventions were five and five weeks of ready-made food box deliveries of isocaloric diets in random order: either LCD (94.5 +- 4.7 g/day) or recommended carbohydrate diet (RCD) (191 +- 19.2 g/day). The outcomes were body weight and body mass index (BMI) standard deviation scores (SDS), body fat percentage assessed by bioimpedance and muscle strength assessed by jumping mechanography at the end of each dietary intervention. The Welch two-sample t-tests were used to determine the difference in outcomes. RESULTS: At the end of the LCD period, the participants had significantly lower body weight and BMI SDS than at the end of the RCD period (61.7 kg vs. 62.6 kg, P < 0.001, and 22.3 kg/m(2) vs. 22.7 kg/m(2), P < 0.001) and (0.84 SD vs. 0.94 SD, P < 0.001, and 0.81 SD vs. 0.91 SD, P < 0.001). The body fat percentage was lower at the end of the LCD period (24.5% vs. 25.3%, P = 0.001). Dynamic muscle functions did not differ significantly at the end of the intervention periods. CONCLUSIONS: We demonstrated that a short-term low-carbohydrate diet is able to decrease body weight, BMI, and decrease the percentage of body fat in CYPwD without negatively affecting their muscle function.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30209 - Paediatrics
Result continuities
Project
<a href="/en/project/NU21-01-00085" target="_blank" >NU21-01-00085: Low-carbohydrate diet in type 1 diabetes: effects on glycemic control and islet autoimmunity</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Journal of Clinical Nutrition
ISSN
0954-3007
e-ISSN
1476-5640
Volume of the periodical
79
Issue of the periodical within the volume
11
Country of publishing house
GB - UNITED KINGDOM
Number of pages
5
Pages from-to
1149-1153
UT code for WoS article
001556446800001
EID of the result in the Scopus database
2-s2.0-105013788043