Biology and pharmacological inhibition of homeodomain-interacting protein kinases

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F25%3A00082491" target="_blank" >RIV/00159816:_____/25:00082491 - isvavai.cz</a>
Result on the web
<a href="https://www.frontiersin.org/journals/chemical-biology/articles/10.3389/fchbi.2025.1441138/full" target="_blank" >https://www.frontiersin.org/journals/chemical-biology/articles/10.3389/fchbi.2025.1441138/full</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/fchbi.2025.1441138" target="_blank" >10.3389/fchbi.2025.1441138</a>

Result language
angličtina
Original language name
Biology and pharmacological inhibition of homeodomain-interacting protein kinases
Original language description
Homeodomain-interacting protein kinases (HIPKs) represent a relatively underexplored sub-family of serine/threonine protein kinases. However, the recently published studies point to the role of HIPKs in the developmental biology and etiology of pathological states, in particular cancer, and potential therapeutic applications of targeting this kinase family. This review summarizes the biology of HIPKs and their heretofore published small-molecule inhibitors. Copyright (C) 2025 Štefek and Paruch.
Czech name
—
Czech description
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Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
10605 - Developmental biology

Project
<a href="/en/project/NW24-08-00280" target="_blank" >NW24-08-00280: Advanced preiclinical progression of new highly selective inhibitors of kinase DDR1</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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