Biology and pharmacological inhibition of homeodomain-interacting protein kinases

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F25%3A00141993" target="_blank" >RIV/00216224:14310/25:00141993 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.3389/fchbi.2025.1441138" target="_blank" >https://doi.org/10.3389/fchbi.2025.1441138</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/fchbi.2025.1441138" target="_blank" >10.3389/fchbi.2025.1441138</a>

Result language
angličtina
Original language name
Biology and pharmacological inhibition of homeodomain-interacting protein kinases
Original language description
Homeodomain-interacting protein kinases (HIPKs) represent a relatively underexplored sub-family of serine/threonine protein kinases. However, the recently published studies point to the role of HIPKs in the developmental biology and etiology of pathological states, in particular cancer, and potential therapeutic applications of targeting this kinase family. This review summarizes the biology of HIPKs and their heretofore published small-molecule inhibitors.
Czech name
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Czech description
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Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
—
OECD FORD branch
30107 - Medicinal chemistry

Project
<a href="/en/project/LM2023052" target="_blank" >LM2023052: National Infrastructure for Chemical Biology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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