COMT polymorphisms in impulsively violent offenders with antisocial personality disorder
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F09%3A4632" target="_blank" >RIV/00216208:11110/09:4632 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/09:10001408 RIV/00064165:_____/09:4632
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
COMT polymorphisms in impulsively violent offenders with antisocial personality disorder
Original language description
OBJECTIVE: The relationship between catechol-O-methyltransferase (COMT) polymorphisms and violent behaviour was tested in highly selected group of non-psychotic violent offenders. METHODS: We conducted an association study comparing 47 male repeatedly sentenced for impulsive violent attacks diagnosed with Antisocial Personality Disorder (APD) with 43 healthy male controls matched on education. Three COMT polymorphisms were analysed: COMT Val(158)Met and COMT Ala(146)Val on exon 4, and untranslated polymorphism on the 611, exon, at the regulatory region of the COMT gene with deletion-insertion character del/C. RESULTS: Logistic regression analysis revealed that while Val(158)Met is not associated with violence in APD, another COMT polymorphism - COMT Ala(146)Val is more frequent among violent offenders with APD (p=0.017).
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FL - Psychiatry, sexology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA206%2F07%2F0779" target="_blank" >GA206/07/0779: Social modulation: genetic variation in the social life of mice</a><br>
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2009
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neuroendocrinology Letters
ISSN
0172-780X
e-ISSN
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Volume of the periodical
30
Issue of the periodical within the volume
6
Country of publishing house
SE - SWEDEN
Number of pages
4
Pages from-to
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UT code for WoS article
000275266400013
EID of the result in the Scopus database
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