Application of the new insertion-deletion polymorphism kit for forensic identification and parentage testing on the Czech population
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A00009640" target="_blank" >RIV/00216208:11110/13:00009640 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11140/13:00009640 RIV/00064165:_____/13:00009640
Result on the web
<a href="http://dx.doi.org/10.1007/s00414-011-0649-3" target="_blank" >http://dx.doi.org/10.1007/s00414-011-0649-3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00414-011-0649-3" target="_blank" >10.1007/s00414-011-0649-3</a>
Alternative languages
Result language
angličtina
Original language name
Application of the new insertion-deletion polymorphism kit for forensic identification and parentage testing on the Czech population
Original language description
We genotyped 55 unrelated Czech individuals. We also genotyped 11 trios to analyze DIPplex Kit (QIAGEN, Germany) suitability for parentage testing. DIPplex Kit contains 30 diallelic autosomal markers. INDELs in DIPplex Kit were tested with linkage disequilibrium test, which showed that they could be treated as independent markers. All 30 loci fulfill Hardy-Weinberg equilibrium. There were several significant differences between Czech and African populations, but no significant ones within European population. Probabilityof a match in the Czech population was 1 in 6.8x1012; combined power of discrimination was 99.9999999999%.Average paternity index was 1.13-1.77 for each locus;combined paternity index reached about 27,000 for a set of 30 loci. The DIPplex kit is useful as an additional panel of markers in paternity cases when mutations in STR polymorphisms are present. For application on degraded or inhibited samples, further optimization of buffer and primer concentrations is needed.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Legal Medicine
ISSN
0937-9827
e-ISSN
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Volume of the periodical
127
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
4
Pages from-to
7-10
UT code for WoS article
000313164100002
EID of the result in the Scopus database
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