In vivo visualization of cells labeled with superparamagnetic iron oxides by a sub-millisecond gradient echo sequence
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10192018" target="_blank" >RIV/00216208:11110/14:10192018 - isvavai.cz</a>
Alternative codes found
RIV/00023001:_____/14:00059036
Result on the web
<a href="http://link.springer.com/article/10.1007%2Fs10334-013-0422-3" target="_blank" >http://link.springer.com/article/10.1007%2Fs10334-013-0422-3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10334-013-0422-3" target="_blank" >10.1007/s10334-013-0422-3</a>
Alternative languages
Result language
angličtina
Original language name
In vivo visualization of cells labeled with superparamagnetic iron oxides by a sub-millisecond gradient echo sequence
Original language description
In vivo magnetic resonance imaging (MRI) of iron-labeled pancreatic islets (PIs) transplanted into the liver is still challenging in humans. The aim of this study was to develop and evaluate a double contrast method for the detection of PIs labeled withsuperparamagnetic iron oxide (SPIO) nanoparticles. Materials and methods: A double-echo three-dimensional (3D) spoiled gradient echo sequence was adapted to yield a sub-millisecond first echo time using variable echo times and highly asymmetric Cartesianreadout. Positive contrast was achieved by conventional and relative image subtraction. Experiments for cell detection efficiency were performed in vitro on gelatin phantoms, in vivo on a Lewis rat and on a patient 6 months after PI transplantation. Results: It was demonstrated that the proposed method can be used for the detection of transplanted PIs with positive contrast in vitro and in vivo. For all experiments, relative subtraction yielded comparable and in some cases better contra
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT13099" target="_blank" >NT13099: Optimalization of the culture conditions of the isolated Langerhans islets for transplantation</a><br>
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Magnetic Resonance Materials in Physics, Biology, and Medicine
ISSN
0968-5243
e-ISSN
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Volume of the periodical
27
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
329-337
UT code for WoS article
000339833300006
EID of the result in the Scopus database
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