The presence of lysyl oxidase-like enzymes in human control and keratoconic corneas

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F16%3A10323217" target="_blank" >RIV/00216208:11110/16:10323217 - isvavai.cz</a>

Alternative codes found

RIV/00064165:_____/16:10323217

Result on the web

<a href="http://dx.doi.org/10.14670/HH-11-649" target="_blank" >http://dx.doi.org/10.14670/HH-11-649</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.14670/HH-11-649" target="_blank" >10.14670/HH-11-649</a>

Result language

angličtina

Original language name

The presence of lysyl oxidase-like enzymes in human control and keratoconic corneas

Original language description

Purpose: Lysyl oxidases, a family comprising lysyl oxidase (LOX) and four LOX-like enzymes (LOXL1-4), catalyse the cross-linking of elastin and collagen fibrils. Keratoconus (KC) is characterized by progressive thinning leading to irregular astigmatism,resulting in significant visual impairment. Although the pathogenesis of KC remains unclear, one of the current hypotheses is based on alterations in the organization and structure of collagen fibrils. To extend existing general knowledge about cross-linking enzymes in the human cornea, in the present study we have focused on the detection of LOXL enzymes.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

<a href="/en/project/LM2010004" target="_blank" >LM2010004: BBMRI_CZ in the building of the Czech part of a large distributed research infrastructure of pan-European importance: the creation and operation of the network of banks of biological material for biomedical research</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Histology and Histopathology

ISSN

0213-3911

e-ISSN

—

Volume of the periodical

31

Issue of the periodical within the volume

1

Country of publishing house

ES - SPAIN

Number of pages

9

Pages from-to

63-71

UT code for WoS article

000366337900006

EID of the result in the Scopus database

2-s2.0-84949035088