Post-prandial endothelial dysfunction is ameliorated following weight loss in obese premenopausal women
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F11%3A00003205" target="_blank" >RIV/00216208:11120/11:00003205 - isvavai.cz</a>
Result on the web
<a href="http://www.medscimonit.com/fulltxt.php?ICID=882048" target="_blank" >http://www.medscimonit.com/fulltxt.php?ICID=882048</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Post-prandial endothelial dysfunction is ameliorated following weight loss in obese premenopausal women
Original language description
Endothelial dysfunction and postprandial hyperglycemia represent independent risk factors for cardiovascular diseases. Obesity is connected with endothelial impairments; however, it is unclear whether weight loss can modify endothelial function during the postprandial period. The aim of this study was to evaluate endothelial response (post-ischemic forearm blood flow, PIFBF) in a fasted state and following ingestion of 75 g glucose before and after very low caloric diet (VLCD). 40 obese premenopausal women (age 39.6- 7.8 years, BMI 34.3-3.2 kg/m2) participated in 4-week very low caloric diet (VLCD, 800 kcal/day). Before and after VLCD, the baseline blood flow and PIFBF were measured using a mercury strain gauge plethysmography in fasting state as wellas 1 hour after ingestion of 75 g glucose. Dietary intervention resulted in a 7% weight loss (p<0.05) and a decrease in insulin resistance index HOMA-IR (2.44-1.25 vs. 1.66-0.81, p<0.05). Before VLCD intervention, PIFBF following oral glu
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD branch
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Result continuities
Project
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Continuities
R - Projekt Ramcoveho programu EK
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Medical Science Monitor
ISSN
1234-1010
e-ISSN
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Volume of the periodical
17
Issue of the periodical within the volume
11
Country of publishing house
PL - POLAND
Number of pages
6
Pages from-to
"CR634"-"CR639"
UT code for WoS article
000298036400020
EID of the result in the Scopus database
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