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Aspects of protein and amino acid metabolism in a model of severe glutamine deficiency in sepsis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F06%3A00004238" target="_blank" >RIV/00216208:11150/06:00004238 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11160/06:00006923

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Aspects of protein and amino acid metabolism in a model of severe glutamine deficiency in sepsis

  • Original language description

    Cecal ligation and puncture resulted in severe septic state with decreased protein synthesis, increased protein breakdown and leucine oxidation. Growth hormone administration did not influence these parameters in septic animals. Alanyl-glutamine prevented a decrease in muscle glutamine, decreased leucine oxidation in both sham-operated and septic rats, and had no effect on protein synthesis and breakdown.

  • Czech name

    Aspekty metabolismu proteinů a aminokyselin u modelu sepse s těžkou glutaminovou deplecí

  • Czech description

    Ligace céka a jeho punkce navodila těžký septický stav provázený sníženou proteosyntézou, zvýšenou proteolýzou a oxidací leucinu. Aplikace růstového hormonu neměla na tyto parametry vliv. Aplikace alanyl-glutaminu zabránila poklesu koncentrace glutaminuve svalu a snížila oxidaci leucinu, neovlivnila však změny v proteosyntéze a proteolýze.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FB - Endocrinology, diabetology, metabolism, nutrition

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NB7611" target="_blank" >NB7611: Effect of growth hormone and glutamine on protein metabolism in isolated skeletal muscle.</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Annals of Nutrition and Metabolism

  • ISSN

    0250-6807

  • e-ISSN

  • Volume of the periodical

    50

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    7

  • Pages from-to

    361-367

  • UT code for WoS article

  • EID of the result in the Scopus database