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Time-dependent changes in concentration of two clinically used acetylcholinesterase reactivators (HI-6 and obidoxime) in rat plasma determined by HPLC techniques after in vivo administration

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F10%3A10072349" target="_blank" >RIV/00216208:11150/10:10072349 - isvavai.cz</a>

  • Alternative codes found

    RIV/60162694:G44__/10:00002317 RIV/44555601:13440/10:00005547

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Time-dependent changes in concentration of two clinically used acetylcholinesterase reactivators (HI-6 and obidoxime) in rat plasma determined by HPLC techniques after in vivo administration

  • Original language description

    A simple and reliable HPLC method for determination of rat plasma levels of clinically used acetylcholinesterase (AChE) reactivators (HI-6 and obidoxime) is presented in our study. HPLC with UV detection presented in our study is a general method which could be applied for quick measurement of bisquaternary AChE reactivators in rat plasma.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/OVUOFVZ200811" target="_blank" >OVUOFVZ200811: Determination of important pharmacokinetic and biochemical parameters and evaluation of blood-brain barrier penetration using drugs introduced to Czech Army</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Analytical Sciences

  • ISSN

    0910-6340

  • e-ISSN

  • Volume of the periodical

    26

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    JP - JAPAN

  • Number of pages

    5

  • Pages from-to

  • UT code for WoS article

    000273653500010

  • EID of the result in the Scopus database