Tetrafluoro-4-pyridyl substituted cyclopentadienyl molybdenum(II) compounds

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11150%2F14%3A10283566" target="_blank" >RIV/00216208:11150/14:10283566 - isvavai.cz</a>
Alternative codes found
RIV/00216275:25310/14:39896485
Result on the web
<a href="http://dx.doi.org/10.1016/j.jorganchem.2013.10.034" target="_blank" >http://dx.doi.org/10.1016/j.jorganchem.2013.10.034</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jorganchem.2013.10.034" target="_blank" >10.1016/j.jorganchem.2013.10.034</a>

Result language
angličtina
Original language name
Tetrafluoro-4-pyridyl substituted cyclopentadienyl molybdenum(II) compounds
Original language description
The allyl molybdenum(II) complex bearing tetrafluoro-4-pyridyl substituted cyclopentadienyl ligand, [(?3-C3H5){?5-C5H3(C5F4N)}Mo(CO)2], was synthesized and characterized by analytical and spectroscopic methods. This compound was found to be suitable precursor for complexes of the type [{?5-C5H4(C5F4N)}Mo(CO)2(NNL)][BF4] where NNL is N,N-chelating ligand. The biological study has shown that these complexes are cytotoxic active toward human leukemia cells MOLT-4. The cytotoxicity strongly depends on nature of the coordinated N,N-chelating ligand. The compounds bearing 1,10-phenanthroline (phen) and 2,2'-biquinoline (bq) are only medium active while the complexes with 4,7-diphenyl-1,10-phenanthroline (4,7-Ph2-phen) and 5-amino-1,10-phenanthroline (5-NH2-phen) show considerably higher activity than cisplatin. This study further describe the X-ray structures of [(?3-C3H5){?5-C5H4(C5F4N)}Mo(CO)2], [(?3-C3H5){?5-C5H3(1,3-C5F4N)2}Mo(CO)2], [{?5-C5H4(C5F4N)}Mo(CO)2(phen)][BF4] and [{?5-C5H4(C5F
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
—

Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)