In vitro anti-proliferative and anti-inflammatory activity of leaf and fruit extracts from Vaccinium bracteatum Thunb.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11160%2F14%3A10281579" target="_blank" >RIV/00216208:11160/14:10281579 - isvavai.cz</a>
Alternative codes found
RIV/61389030:_____/14:00433742 RIV/60460709:41340/14:62902
Result on the web
<a href="http://www.pjps.pk/wp-content/uploads/pdfs/27/1/Paper-15.pdf" target="_blank" >http://www.pjps.pk/wp-content/uploads/pdfs/27/1/Paper-15.pdf</a>
DOI - Digital Object Identifier
—
Alternative languages
Result language
angličtina
Original language name
In vitro anti-proliferative and anti-inflammatory activity of leaf and fruit extracts from Vaccinium bracteatum Thunb.
Original language description
The aim of this study was to evaluate in vitro anti-proliferative (tested on MCF-7, MDA-MB-231, and MCF-10A cell lines) and anti-inflammatory (evaluated as inhibition of prostaglandin E-2 synthesis catalyzed by cyclooxygenase-2) effect of various extracts from Vaccinium bracteatum leaves and fruits. The highest anti-proliferative effect possessed leaf dichloromethane extract with IC50 values ranging from 93 to 198 mu g/mL. In the case of cyclooxygenase-2 inhibition, n-hexane, dichloromethane, and ethanol fruit extracts showed the best activity with IC50 values = 2.0, 5.4, and 12.7 mu g/mL, respectively. These results indicate that V bracteatum leaves and fruits could be useful source of anti-cancer and anti-inflammatory compounds.
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
—
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Pakistan Journal of Pharmaceutical Sciences
ISSN
1011-601X
e-ISSN
—
Volume of the periodical
27
Issue of the periodical within the volume
1
Country of publishing house
PK - PAKISTAN
Number of pages
4
Pages from-to
103-106
UT code for WoS article
000346327000015
EID of the result in the Scopus database
—