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Voltammetric DNA biosensor based on a microcrystalline natural graphite-polystyrene composite transducer

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F12%3A10126733" target="_blank" >RIV/00216208:11310/12:10126733 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.proche.2012.10.130" target="_blank" >http://dx.doi.org/10.1016/j.proche.2012.10.130</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.proche.2012.10.130" target="_blank" >10.1016/j.proche.2012.10.130</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Voltammetric DNA biosensor based on a microcrystalline natural graphite-polystyrene composite transducer

  • Original language description

    New voltammetric DNA biosensor based on a microcrystalline natural graphite-polystyrene composite film in the role of a transducer was used for the investigation of the interaction between model carcinogenic substance (2-aminofluorene; one of the most extensively studied examples of the aromatic amine class of carcinogens) and calf thymus double-stranded DNA (dsDNA). The layer of dsDNA immobilized at the electrode surface was utilized as a biocomponent responsive interface. The biosensor was characterized regarding the detection of DNA damage (induced by direct interaction with 2-aminofluorene) using square wave voltammetric responses of the guanine and adenine moieties and cyclic voltammetric responses of the anionic redox indicator [Fe(CN)6]4-/3- present in the solution.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CG - Electrochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GBP206%2F12%2FG151" target="_blank" >GBP206/12/G151: Center of novel approaches to bioanalysis and molecular diagnostics</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Procedia Chemistry [online]

  • ISSN

    1876-6196

  • e-ISSN

  • Volume of the periodical

    6

  • Issue of the periodical within the volume

    April

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    8

  • Pages from-to

    52-59

  • UT code for WoS article

    000313216900008

  • EID of the result in the Scopus database