Benzofurazane as a New Redox Label for Electrochemical Detection of DNA: Towards Multipotential Redox Coding of DNA Bases
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F13%3A10192950" target="_blank" >RIV/00216208:11310/13:10192950 - isvavai.cz</a>
Alternative codes found
RIV/68081707:_____/13:00399797 RIV/61388963:_____/13:00399797 RIV/00216224:14740/13:00067004
Result on the web
<a href="http://dx.doi.org/10.1002/chem.201301868" target="_blank" >http://dx.doi.org/10.1002/chem.201301868</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/chem.201301868" target="_blank" >10.1002/chem.201301868</a>
Alternative languages
Result language
angličtina
Original language name
Benzofurazane as a New Redox Label for Electrochemical Detection of DNA: Towards Multipotential Redox Coding of DNA Bases
Original language description
Benzofurazane has been attached to nucleosides and dNTPs, either directly or through an acetylene linker, as a new redox label for electrochemical analysis of nucleotide sequences. Primer extension incorporation of the benzofurazane-modified dNTPs by polymerases has been developed for the construction of labeled oligonucleotide probes. In combination with nitrophenyl and aminophenyl labels, we have successfully developed a three-potential coding of DNA bases and have explored the relevant electrochemical potentials. The combination of benzofurazane and nitrophenyl reducible labels has proved to be excellent for ratiometric analysis of nucleotide sequences and is suitable for bioanalytical applications.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Chemistry - A European Journal
ISSN
0947-6539
e-ISSN
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Volume of the periodical
19
Issue of the periodical within the volume
38
Country of publishing house
GB - UNITED KINGDOM
Number of pages
12
Pages from-to
12720-12731
UT code for WoS article
000324316300025
EID of the result in the Scopus database
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