Effect of the type of commercially available mixed-mode stationary phases on the retention of pharmaceutically important acidic and neutral compounds using different compositions of mobile phase
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F22%3A10452276" target="_blank" >RIV/00216208:11310/22:10452276 - isvavai.cz</a>
Result on the web
<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=l7cee60HnL" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=l7cee60HnL</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00706-022-02960-6" target="_blank" >10.1007/s00706-022-02960-6</a>
Alternative languages
Result language
angličtina
Original language name
Effect of the type of commercially available mixed-mode stationary phases on the retention of pharmaceutically important acidic and neutral compounds using different compositions of mobile phase
Original language description
Four different columns with mixed-mode properties were used to investigate the retention behavior of four acidic compounds (ascorbic, nicotinic, p-toluenesulfonic, and p-hydroxybenzenesulfonic acids) and two neutral compounds (dexamethasone and paracetamol). The effect of mobile phase composition (acetonitrile content and buffer pH) on the retention of the analytes was studied to better understand the separation role of an ion-exchange group position within a stationary phase for acidic analytes. The impact of C18 hydrophobic moiety, identical for all the tested stationary phases, was studied on retention of two neutral compounds via selected parameters characterizing the investigated stationary phases. The results obtained were compared and discussed with data previously reached using an Acclaim(TM) WAX-1 mixed-mode column.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
—
Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Monatshefte für Chemie - Chemical Monthly
ISSN
0026-9247
e-ISSN
1434-4475
Volume of the periodical
153
Issue of the periodical within the volume
9
Country of publishing house
AT - AUSTRIA
Number of pages
7
Pages from-to
719-725
UT code for WoS article
000830256900001
EID of the result in the Scopus database
2-s2.0-85134977261