Changes of immunofluorescence staining for ECM molecules in the satellite cells of rat dorsal root ganglia following a chronic constriction injury of the peripheral nerve

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F03%3A00008386" target="_blank" >RIV/00216224:14110/03:00008386 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Changes of immunofluorescence staining for ECM molecules in the satellite cells of rat dorsal root ganglia following a chronic constriction injury of the peripheral nerve

Original language description

We have investigated immunostaining for some ECM molecules ( chondroitin sulfate, tenascin, thrombospondin, fibronectin) in the DRG satellite cells following CCI of the peripheral nerve. The experimental CCI was applied ipsilaterally on the spinal nerveand the sciatic nerve of Wistar rats (12 females, 280g). Both ipsilateral and contralateral DRG (L4-L5) were removed 1, 2, 3, 5 weeks after the operation. The immunofluorescence staining for ECM molecules was compared in the sections through ipsilateraland contralateral DRG by an image analysis system. The satellite cell sheaths of ipsilateral DRG (L4-L5) displayed a higher brightness of immunofluorescence staining for investigated ECM molecules in comparison to the contralateral ones. The changes weremore noticeable after CCI applied near to DRG (4mm) than in longer distance (40mm). An increased immunostaining for the ECM molecules in the satellite cells following CCI of peripheral nerve suggested that the changes may be implicated i

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

<a href="/en/project/GA309%2F00%2F0407" target="_blank" >GA309/00/0407: Cellular and extracellular environment for the axon regeneration following injury of the spinal roots and peripheral nerves</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2003

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Glia Suppl

ISSN

0894-1491

e-ISSN

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Volume of the periodical

2

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

1

Pages from-to

36

UT code for WoS article

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EID of the result in the Scopus database

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