Quantitative immunofluorescence for BDNF, NGF and NT-3 in Schwann cells of the spinal roots and peripheral nerve.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F03%3A00008387" target="_blank" >RIV/00216224:14110/03:00008387 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Quantitative immunofluorescence for BDNF, NGF and NT-3 in Schwann cells of the spinal roots and peripheral nerve.

Original language description

Immunofluorescence intensity for BDNF, NGF and NT-3 was higher in the Schwann cells of cutaneous than motor branches of the intact femoral nerve. On the other hand, a higher intensity for BDNF and NT-3 immunofluorescence was measured in the Schwann cellsof the intact dorsal than ventral roots while no difference was found for NFG immunostaining. Two weeks after rhizotomy or nerve transection immunofluorescence intensity for investigated neurotrophins was significantly higher in all distal Schwann cellsin comparison to the ones of the intact roots or nerves. In addition, intensity of immunofluorescence for BDNF, NGF and NT-3 was very similar in the Schwann cells of both motor and cutaneous branches two weeks after transection of the femoral nerve. Comparing the Schwann cells of rhizotomized roots the immunofluorescence was significantly higher in the ventral than dorsal roots. The results revealed that the axotomy-induced up-regulation of neurotrophins is different in the Schwann cell

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

<a href="/en/project/GA309%2F00%2F0407" target="_blank" >GA309/00/0407: Cellular and extracellular environment for the axon regeneration following injury of the spinal roots and peripheral nerves</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2003

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

The Histochemical Journal

ISSN

0018-2214

e-ISSN

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Volume of the periodical

34

Issue of the periodical within the volume

1

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

1

Pages from-to

451

UT code for WoS article

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EID of the result in the Scopus database

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