Value of PCR in surgically treated patients with staphylococcal infective endocarditis: a 4-year retrospective study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F12%3A00059130" target="_blank" >RIV/00216224:14110/12:00059130 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11150/12:10124819 RIV/00179906:_____/12:10124819 RIV/00023001:_____/12:00055972

Result on the web

<a href="http://dx.doi.org/10.1007/s10096-011-1427-3" target="_blank" >http://dx.doi.org/10.1007/s10096-011-1427-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10096-011-1427-3" target="_blank" >10.1007/s10096-011-1427-3</a>

Result language

angličtina

Original language name

Value of PCR in surgically treated patients with staphylococcal infective endocarditis: a 4-year retrospective study

Original language description

The aim of the study was to establish a diagnostic value for broad-range polymerase chain reaction (br-PCR) and staphylococci-specific multiplex PCR (ssm-PCR) performed on surgical material from patients with staphylococcal infective endocarditis (IE). Data were analysed retrospectively from 60 patients with suspected staphylococcal IE and 59 controls who were surgically treated at three cardiosurgery centres over 4 years. Both PCR tests showed high agreement and could be aggregated. In patients with definite and rejected IE, the clinical sensitivity and specificity of PCR reached 89 and 95%, respectively. Tissue culture (TC) and PCR agreed with blood culture (BC) in 29% and 67% of IE cases. TC helped to determine aetiology in five BC negative cases while PCR aided in nine cases. Out of 52 patients with conclusive staphylococcal IE, 40 were diagnosed with S. aureus and 12 with coagulasenegative staphylococci. PCR was shown to be highly superior to TC in confirming preoperative diagnosi

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

<a href="/en/project/2B08060" target="_blank" >2B08060: Development of diagnostics and treatment of serious heart and vascular diseases using genomic and proteomic approaches</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Journal of Clinical Microbiology & Infectious Diseases

ISSN

0934-9723

e-ISSN

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Volume of the periodical

31

Issue of the periodical within the volume

6

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

1187-1194

UT code for WoS article

000303878400040

EID of the result in the Scopus database

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