Polymorphisms in HLA-related genes and psoriasis heredity in patients with psoriasis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F13%3A00069381" target="_blank" >RIV/00216224:14110/13:00069381 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/13:#0002071 RIV/00159816:_____/13:00060658
Result on the web
<a href="http://dx.doi.org/10.1111/ijd.12213" target="_blank" >http://dx.doi.org/10.1111/ijd.12213</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/ijd.12213" target="_blank" >10.1111/ijd.12213</a>
Alternative languages
Result language
angličtina
Original language name
Polymorphisms in HLA-related genes and psoriasis heredity in patients with psoriasis
Original language description
Background The aim of this study was to investigate possible associations of the five DNA polymorphic genotypes in the HLA region (transporter associated with antigen processing [TAP1; TAP1333 a/b, TAP1637 c/d], the HLA-DRB1*1501-rs3135388, tumor necrosis factor [TNF] [-238 G/A] and NcoI TNF) with characteristics of family history in patients with psoriasis vulgaris. Materials and methods A total of 201 Czech patients with psoriasis were enrolled in the study. The patients were genotyped for the five common polymorphisms in TAP1, TNF, and TNF genes (6p21.3) using the polymerase chain reaction-restriction fragment length polymorphism-based methodology. Results We observed significantly higher prevalence of Ile333Ile TAP1 allele in patients whose first-degree relatives had a positive family history of psoriasis (P-a=0.04). No differences related to family history of psoriasis were observed in HLA-DRB1*1501 polymorphism.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FO - Dermatology and venereology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Dermatology
ISSN
0011-9059
e-ISSN
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Volume of the periodical
52
Issue of the periodical within the volume
8
Country of publishing house
US - UNITED STATES
Number of pages
6
Pages from-to
960-965
UT code for WoS article
000322015000009
EID of the result in the Scopus database
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