Novel biophysical determination of miRNAs related to prostate and head and neck cancers
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00083124" target="_blank" >RIV/00216224:14110/15:00083124 - isvavai.cz</a>
Alternative codes found
RIV/68081707:_____/15:00446309 RIV/00216305:26620/15:PU117292
Result on the web
<a href="http://dx.doi.org/10.1007/s00249-015-1008-y" target="_blank" >http://dx.doi.org/10.1007/s00249-015-1008-y</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00249-015-1008-y" target="_blank" >10.1007/s00249-015-1008-y</a>
Alternative languages
Result language
angličtina
Original language name
Novel biophysical determination of miRNAs related to prostate and head and neck cancers
Original language description
In this study we have chosen a new approach and characterized three miRNAs (miR-23a, miR-34a and miR-320a) related to prostate cancer and head and neck cancer by spectral (circular dichroic and UV-absorption spectra) and electrochemical (voltammetry at graphite and mercury electrodes) methods. The spectral and voltammetric results, reflecting different nucleotide sequences of miRNAs, were complemented by the results of DNAs(U) having the same oligonucleotide sequences as miRNAs. The effect of the substitution of ribose for deoxyribose was shown and structural diversity was confirmed. The stability of RNA and DNA(U) was studied using CD and UV-absorption spectroscopy and melting points were calculated. MiRNA-320a with the highest content of guanine provided the highest melting point.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BO - Biophysics
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Biophysics Journal With Biophysics Letters
ISSN
0175-7571
e-ISSN
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Volume of the periodical
44
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
131-138
UT code for WoS article
000351237400004
EID of the result in the Scopus database
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