Moving towards Normalization of haemostasis and health equity: Evolving treatment goals for haemophilia A

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F24%3A00137905" target="_blank" >RIV/00216224:14110/24:00137905 - isvavai.cz</a>

Result on the web

<a href="https://onlinelibrary.wiley.com/doi/10.1111/hae.15031" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1111/hae.15031</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/hae.15031" target="_blank" >10.1111/hae.15031</a>

Result language

angličtina

Original language name

Moving towards Normalization of haemostasis and health equity: Evolving treatment goals for haemophilia A

Original language description

BackgroundTreatment options for people with haemophilia are evolving at a rapid pace and a range of prophylactic treatment options using various technologies are currently available, each with their own distinct safety and efficacy profile.Treatment goalsThe access to replacement therapy and prophylaxis has driven a dramatic reduction in mortality and resultant increase in life expectancy. Beyond this, the abolition of bleeds and preservation of joint health represent the expected, but rarely attained, goals of haemophilia treatment and care. These outcomes also do not address the complexity of health-related quality of life impacted by haemophilia and its treatment.ConclusionCapitalizing on the major potential of therapeutic innovations, 'Normalization' of haemostasis, as a concept, should include the aspiration of enabling individuals to live as normal a life as possible, free from haemophilia-imposed limitations. To achieve this-being supported by the data reviewed in this manuscript-the concept of haemostatic and life Normalization needs to be explored and debated within the wider multidisciplinary teams and haemophilia community.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30205 - Hematology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Haemophilia

ISSN

1351-8216

e-ISSN

1365-2516

Volume of the periodical

30

Issue of the periodical within the volume

5

Country of publishing house

US - UNITED STATES

Number of pages

6

Pages from-to

1109-1114

UT code for WoS article

001268201200001

EID of the result in the Scopus database

2-s2.0-85198144412