Disruption of retinoid transport, metabolism and signaling by environmental pollutants

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F08%3A00025288" target="_blank" >RIV/00216224:14310/08:00025288 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Disruption of retinoid transport, metabolism and signaling by environmental pollutants

Original language description

Disruption of retinoid transport, metabolism and signaling by environmental pollutants. - a review. Although the assessment of circulatory levels of retinoids has become a widely used biomarker of exposure to environmental pollutants, the adverse effectscaused by imbalance of the retinoid metabolism and signaling in wildlife are not known in detail. Retinoids play an important role in controlling such vital processes as morphogenesis, development, reproduction or apoptosis. Unlike other signaling molecules, retinoids are not strictly endogenous but they are derived from dietary sources of vitamin A or its precursors and thus they are sometimes referred to as dietary hormones. Some environmental pollutants that affect embryogenesis, immunity or epithelial functions were also shown to interfere with retinoid metabolism and signaling in animals. This suggests that at least some of their toxic effects may be associated with interaction with the retinoid metabolism, transport or signal tra

Czech name

Narušení transportu, metabolismu a signálování retinoidů kontaminanty životního prostředí

Czech description

Narušení transportu, metabolismu a signálování retinoidů kontaminanty životního prostředí - review

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

DN - Environmental impact on health

OECD FORD branch

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Project

<a href="/en/project/GP525%2F05%2FP160" target="_blank" >GP525/05/P160: In vitro models for study of endocrine disruption - effects of traditional and new types of persistent organic pollutants</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2008

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Environment International

ISSN

0160-4120

e-ISSN

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Volume of the periodical

34

Issue of the periodical within the volume

6

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

16

Pages from-to

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UT code for WoS article

000259162000018

EID of the result in the Scopus database

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