Molecular characterization of a new efficiently transducing bacteriophage identified in meticillin-resistant Staphylococcus aureus
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F16%3A00087677" target="_blank" >RIV/00216224:14310/16:00087677 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1099/jgv.0.000329" target="_blank" >http://dx.doi.org/10.1099/jgv.0.000329</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1099/jgv.0.000329" target="_blank" >10.1099/jgv.0.000329</a>
Alternative languages
Result language
angličtina
Original language name
Molecular characterization of a new efficiently transducing bacteriophage identified in meticillin-resistant Staphylococcus aureus
Original language description
In Staphylococcus aureus, generalized transduction mediated by temperate bacteriophages represents a highly efficient way of transferring antibiotic resistance genes between strains. In the present study, we identified and characterized in detail a new efficiently transducing bacteriophage of the family Siphoviridae, designated phiJB, which resides as a prophage in the meticillin-resistant S. aureus (MRSA) strain Jevons B. Whole-genome sequencing followed by detailed in silico analysis uncovered a linear dsDNA genome consisting of 43012 bp and comprising 70 ORFs, of which approximately 40 encoded proteins with unknown function. A global genome alignment of phiJB and other efficiently transducing phages phi11, phi53, phi80, phi80alpha and phiNM4 showed a high degree of homology with phiNM4 and substantial differences with regard to other phages.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/QJ1510216" target="_blank" >QJ1510216: Phage therapy of infections caused by Staphylococcus aureus in livestock breeding</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of General Virology
ISSN
0022-1317
e-ISSN
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Volume of the periodical
97
Issue of the periodical within the volume
January
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
258-267
UT code for WoS article
000372062500027
EID of the result in the Scopus database
2-s2.0-84957596876