(SALD) ICP-MS to examine the effect of copper on wedelolactone cytotoxicity towards breast cancer cells

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F16%3A00088260" target="_blank" >RIV/00216224:14310/16:00088260 - isvavai.cz</a>
Result on the web
—
DOI - Digital Object Identifier
—

Result language
angličtina
Original language name
(SALD) ICP-MS to examine the effect of copper on wedelolactone cytotoxicity towards breast cancer cells
Original language description
In this study, the effect of copper on wedelolactone cytotoxicity towards breast cancer cells was examined. To monitor copper loading of cells, SALD ICP-MS (substrate assisted laser desorption inductively coupled plasma mass spectrometry) and conventional nebulizing ICP-MS analysis were used. The SALD technique provided direct and fast analysis of liquid samples in the form of dried droplets with minimal sample preparation and sub-microliter sample volume requirement. Furthermore, the SALD allowed direct analysis of samples in organic solvents, which could not be directly nebulised to ICP-MS. The experiments showed that copper chelation can drastically reduce wedelolactone cytotoxicity.
Czech name
—
Czech description
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
CECE 2016 International Interdisciplinary Meeting on Bioanalysis
ISBN
9788090495944
ISSN
—
e-ISSN
—
Number of pages
4
Pages from-to
248-251
Publisher name
Neuveden
Place of publication
Brno (ČR)
Event location
hotel Continental Brno, ČR
Event date
Oct 17, 2016
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
—

Similar results(10)